Mechanical strength of calcium phosphate cement in vivo and in vitro

Effects of silica addition on the chemical, mechanical and biological properties of a new α-Tricalcium Phosphate/Tricalcium Silicate Cement

“…One of the most important formulations is based on a-tricalcium phosphate [a-Ca 3 (PO 4 ) 2 ; a-TCP], which sets in situ and forms a calcium-deficient hydroxyapatite [Ca 9 (HPO 4 )(PO 4 ) 5 (OH); CDHA] when hydrated 3 . However, it is not very strong under compression 4 and its mechanical strength is low when compared to that of cortical bone 5 , limiting its application to areas subjected to low mechanical loads 6 . In view of the excellent bioresorbability of CDHA, researchers have focused their efforts on overcoming the mechanical weakness of calcium phosphate cements by using different fillers, fibers and reinforcing additives that lead to the formation of various multiphase composites, based on the idea that the filler in the matrix may eliminate crack propagation 7 .…”

Assessment of bone healing and hypoesthesia in the upper lip after Le Fort I osteotomy with self-setting α-tricalcium phosphate and absorbable plates

“…Monma et al (1988) have originally developed a self-setting cement-type calcium phosphate material consisting of α-TCP, dicalcium phosphate dibasic (DCPD) and tetracalcium phosphate monoxide (TeCP). According to their extensive studies, this cement-type material could be refined, demonstrating better biocompatibility and direct integration to bone without any participation of peripheral soft tissue (Kurashina et al,1997a,b;Yamamoto et al, 1998;Yuan et al, 2000). As it is free of infiltration over time of residual monomers of methacrylate resin, which has long been used for orthopedic treatment, this self-setting cement came to be rapidly targeted for clinical use in Japan.…”

Composite resins: a review of adhesive failure from enzymatic degradation

“…However, the identification of several cathepsins in dentin can elucidate the potential cathepsin-MMP interactions collagen degradation also in the hybrid layer 17 . to emphasize that this is a natural product that has no side effects.It is described that the minimum inhibitory concentration of the substance to inhibit MMP-2 and MMP-9 is 0.00075% a n d t h e r e f o r e l o w e r t h a n chlorhexidine 9,11,19,30 .…”