2024
DOI: 10.3389/fendo.2024.1492610
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Mechanism and application prospect of ferroptosis inhibitors in improving osteoporosis

Jing Wang,
TingRui Chen,
Fei Gao

Abstract: Osteoporosis, a prevalent bone metabolic disorder, has emerged as a pressing global public health concern. Recent studies have illuminated a crucial link between ferroptosis and the pathogenesis of osteoporosis. Nevertheless, the intricate mechanisms underlying the role of ferroptosis in this condition remain largely unexplored. Therefore, this article comprehensively reviews the regulatory mechanisms of ferroptosis and the modulating effects on the development and progression of osteoporosis, as reported in r… Show more

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