BackgroundRapid economic growth in China has led to significant resource and environmental challenges, particularly in less economically developed regions. This study aims to identify effective strategies for achieving green, low-carbon development in these regions during the economic transition.MethodsWe employed the Fuzzy-Set Qualitative Comparative Analysis (fsQCA) method to scrutinize the impact of economic, demographic, industrial, and technological factors on low-carbon development across a selection of Chinese provinces, including Qinghai, Hunan, Beijing, Shanghai, Tianjin, Hainan, and Chongqing. This approach facilitates a nuanced exploration of the multifaceted determinants of low-carbon progress within the regional contexts of China.ResultsThe study identified three distinct paths to low-carbon development, each with unique prioritization characteristics. These paths are the traditional early low-carbon path, the semi-modernized mid-carbon path, and the post-modernized low-carbon path. Each path offers tailored strategies for less developed regions to enhance their environmental innovation capacity and global competitiveness.ConclusionThis research contributes a novel perspective for regional sustainable development in China by offering tailored low-carbon development strategies for less developed regions. The findings suggest that region-specific strategies, aligned with developmental stages and characteristics, are essential for ensuring balanced economic, social, and environmental development.