Mechanism of Action of an Antiseptic, Anti-odor Mouthwash

Pitts, Gary; Brogdon, C.; Hu, Ling; Masurat, Thomas; Pianotti, Roland S.; Schumann, Pascale

doi:10.1177/00220345830620061001

Cited by 74 publications

(63 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Anti-plaque and anti-gingivitis activity has been demonstrated in several studies [for details see a meta-analysis published by Gunsolley 52 (2006)]. An EO mouthrinse was able to reduce the offensive gases present in morning bad breath as measured by a sulfide monitor, 50 a result that is in agreement with those of a previous short-term study, 53 in which the results indicated a reduction of the organoleptic scores by EOs, which caused a sustained reduction in the plaque odorigenic bacteria, unlike the placebo. An argument was made that the re-odoration was important to the overall activity of the product only for about 30 min after treatment and, at post-treatment times of 60-180 min, the anti-odor activity of the product was due to its anti-microbial action.…”

Section: Essential Oilssupporting

confidence: 80%

“…10 Substrates for volatile sulfide compounds production are sulfur-containing amino-acids such as cysteine, cystine and methionine present in saliva or gingival fluid. 11 Several microorganisms recovered from periodontal lesions of gingivitis and Braz Oral Res 2008;22(Spec Iss 1): [44][45][46][47][48][49][50][51][52][53][54] periodontitis are related to produce large amounts of these volatile sulfur compounds. 10 The bacterial interactions are most likely to occur in the gingival crevices and periodontal pockets, but oral malodor can also arise from the posterior dorsal tongue.…”

Section: Halitosis and The Presence Of Oral Microorganismsmentioning

confidence: 99%

“…An argument was made that the re-odoration was important to the overall activity of the product only for about 30 min after treatment and, at post-treatment times of 60-180 min, the anti-odor activity of the product was due to its anti-microbial action. 53 That conclusion became the basis for the premise that anti-VSC agents would succeed if they had an antimicrobial component.…”

Section: Essential Oilsmentioning

confidence: 99%

See 2 more Smart Citations

Halitosis: a review of associated factors and therapeutic approach

Barbosa²,

2008

View full text Add to dashboard Cite

Halitosis or bad breath is an oral health condition characterized by unpleasant odors emanating consistently from the oral cavity. The origin of halitosis may be related both to systemic and oral conditions, but a large percentage of cases, about 85%, are generally related to an oral cause. Causes include certain foods, poor oral health care, improper cleaning of dentures, dry mouth, tobacco products and medical conditions. Oral causes are related to deep carious lesions, periodontal disease, oral infections, peri-implant disease, pericoronitis, mucosal ulcerations, impacted food or debris and, mainly, tongue coating. Thus, the aim of the present review was to describe the etiological factors, prevalence data and the therapeutic mechanical and chemical approaches related to halitosis. In general, halitosis most often results from the microbial degradation of oral organic substrates including volatile sulfur compounds (VSC). So far, there are few studies evaluating the prevalence of oral malodor in the world population. These studies reported rates ranging from 22% to more than 50%. The mechanical and chemical treatment of halitosis has been addressed by several studies in the past four decades. Many authors agree that the solution of halitosis problems must include the reduction of the intraoral bacterial load and/or the conversion of VSC to nonvolatile substrates. This could be achieved by therapy procedures that reduce the amount of microorganisms and substrates, especially on the tongue.

show abstract

Section: Essential Oilssupporting

confidence: 80%

Section: Halitosis and The Presence Of Oral Microorganismsmentioning

confidence: 99%

Section: Essential Oilsmentioning

confidence: 99%

See 1 more Smart Citation

Halitosis: a review of associated factors and therapeutic approach

Barbosa²,

2008

View full text Add to dashboard Cite

show abstract

“…It has been found only relatively effective against oral malodour (25% reduction vs. 10% for placebo). 77 Shinada K et al showed that a mouthwash containing ClO 2 improved morning bad breath and reduced the concentrations of H 2 S, CH 3 SH and (CH 3 ) in healthy subjects. Moreover ClO 2 mouthwash used over a 7-day period was effective in reducing.…”

Section: Treatmentmentioning

confidence: 99%

HALITOSIS – A Social Malady

Kukkamalla¹,

Cornelio²,

Bhat³

et al. 2014

IOSRJDMS

View full text Add to dashboard Cite

“…Most commercially available mouthrinses only mask odors and have only a temporary reducing effect on the total number of microorganisms in the oral cavity. Even when these mouthrinses do contain antiseptic substances, the effects are usually not long-lasting [54,55].…”

Section: Treatment Of Oral Malodormentioning

confidence: 99%

Oral Malodor: A Common Oral Problem

Saini¹

2012

J Bioengineer & Biomedical Sci

View full text Add to dashboard Cite

Oral malodor, also called halitosis or bad breath, is universally experienced condition that has a variety of etiologic factors. It is extremely common and majority of adult population have had it at some point in time. Halitosis may be physiological, pathological, and sometimes psychological also. Although numerous non-oral sites and many different causes have been correlated to bad breath, an estimated 80 percent to 90 percent of all bad breath odors originate from the mouth, and bacteria are directly responsible for most of the offensive gases. Specific groups of bacteria have been identified with the production of oral malodor, in particular, gram-negative, anaerobic bacteria. The unpleasant smell of breath mainly originates from volatile sulfide compounds (VSCs), especially hydrogen sulfide (H 2 S), methylmercaptan (CH3SH), and dimethylsulfide [(CH 3 ) 2 S] result from the proteolytic degradation of peptides present in saliva, shed epithelium, food debris and gingival crevicular fluid (GCF). This article reviews the etiology, diagnosis, and treatment of oral malodor and gives a brief description of Halitosis Associated Life-quality Test (HALT) questionnaire, a specific 20-item quality-of-life measure for halitosis. The tongue plaque coatingResearch suggests that the tongue is the primary site in the production of oral malodor. The dorsoposterior surface of the tongue has been identified as the principal location for the intraoral generation of VSCs [12]. A variety of index systems for tongue coating has been developed over the years. Miyazaki et al divides the tongue into three sections and the presence or absence of tongue coating is registered as follows: Score 0 = none visible, Score 1 = less than one third of tongue dorsum is covered, Score 2 = between one and two thirds, Score 3 = more than two thirds [13]. Winkel et al divides the tongue into six sections, three in the posterior and three in the anterior part of the tongue. Each sextant is categorized as: Score 0 = no coating present, Score 1 = presence of a light coating, Score 2 = presence of a distinct coating. The resulting Winkel tongue coating index (WTCI) is obtained by adding all six scores (Figure 1) [14].

show abstract

Mechanism of Action of an Antiseptic, Anti-odor Mouthwash

Cited by 74 publications

References 17 publications

Halitosis: a review of associated factors and therapeutic approach

Halitosis: a review of associated factors and therapeutic approach

HALITOSIS – A Social Malady

Oral Malodor: A Common Oral Problem

Contact Info

Product

Resources

About