2024
DOI: 10.3389/fphar.2024.1397703
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Mechanism of baicalein in treatment of castration-resistant prostate cancer based on network pharmacology and cell experiments

Baokai Dou,
Yingjie Cui,
Qianqian Zhou
et al.

Abstract: ObjectiveBaicalein, one of the most abundant flavonoids found in Chinese herb Scutellaria baicalensis Georgi, exhibits pharmacological activities against various cancers. However, the precise pharmacological mechanism of baicalein in treating castration-resistant prostate cancer (CRPC) remains elusive. This study aimed to elucidate the potential mechanism of baicalein against CRPC through a combination of network pharmacology and experimental approaches, thereby providing new avenues for research in CRPC treat… Show more

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