In the ongoing world trends focusing on the ecological issue, corporate social responsibilities, sustainable development goals, the current business could not be competitive without the implementation of the innovations. Besides, the application of changes contributes to the relevant transformation of the business model, considering the worldwide trends. The paper deals with the analysis of the leading scientific trends in analysing of the sustainable business models and innovations. In the paper, the authors used the bibliometric analysis of the scientific papers from Web of Science and Scopus. The main limitation to select scientific papers were as follows: published for 2000-2019 years; the language of the paper – English; papers which contain keywords – sustainable, business model and innovations. For the analysis, the VOSviewer, Scopus and Web of Science tools were used by the authors. Tools from the scientific databases allowed to identify the main parameters of the scientific publications: quantity, dynamic, country, the most cited papers, etc. VOSviewer allowed visualising the main scientific clusters which analysed the sustainable business model. Considering the findings, the rapid increase of articles on the sustainable business model was in 2000. The authors identified 13 clusters; three of them had strong linking. The most significant cluster contained focused on innovations, the second – on corporate social responsibilities and environmental management, the third cluster – on cleaner production as a core element of a sustainable business model. The tendency of scientific investigation allowed concluding that sustainable business model could not be without a complex system of innovations, corporate social responsibilities and cleaner production.