Mechanism of Phosphate Adsorption to a Three-Dimensional Structure of Boehmite in the Presence of Bovine Serum Albumin

Ookubo, Akira; Nishida, Mikio; Ooi, Kenta; Ishida, Kenji; Hashimura, Yuko; Ikawa, Atsuya; Yoshimura, Yoshiyuki; Kawada, Jun

doi:10.1002/jps.2600820714

Cited by 6 publications

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References 21 publications

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“…The OCP values increase as a result of the additional layer formation on the catheter surface, which consists of the components of the PBS solution (mainly K + and N a + ). On the other hand, a slight decrease in the OPC values is related to the phosphate (P O 3 − 4 ) adsorption, which is favourable in the BSA adsorption mechanism [27]. The presence of the above-mentioned elements was confirmed in further EDS analyses.…”

Section: The Open Circuit Potential Values (Ocp)mentioning

confidence: 64%

Impedimetric method to monitor biological layer formation on central venous catheters for hemodialysis made of carbothane

Paradowska

Nycz

Arkusz

et al. 2018

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Abstract. The aim of the study was to specify by an impedimetric method the changes observed on the inner wall of central venous catheters for hemodialysis leading to the formation of a biological film. To evaluate these changes a patient-dialyzer model was built in which experimental parameters were kept closely similar to the clinical conditions of hemodialysis. The impedance spectra and SEM/EDS analysis of the biological layer deposited on the inner surface of the distal part of the catheter gave an insight into the structure of film formation and its chemical composition. Since an early detection of biofilm formation inside the distal part of the catheter is crucial for the safety of medical treatment and it usually prompts the implementation of antibiotic therapy. Developed impedimetric method can minimize the risk of infection and ensure the continuity of treatment.

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Section: The Open Circuit Potential Values (Ocp)mentioning

confidence: 64%

Impedimetric method to monitor biological layer formation on central venous catheters for hemodialysis made of carbothane

Paradowska

Nycz

Arkusz

et al. 2018

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“…7 Recently, we prepared a new microcrystalline compound of aluminum oxide hydroxide (boehmite), tentatively named PT-A, and tested it as a replacement for ALG. [8][9][10] PT-A is a spherical particle with a porous structure; it was found to have better phosphate adsorptivity and chemical stability than ALG. An equilibrium adsorption study has shown that phosphates diffuse freely into the smaller tunnels of PT-A even when the external surface is covered with bovine serum albumin (BSA).…”

mentioning

confidence: 98%

“…8 The main site for phosphate adsorption is in the micropores of PT-A. 9 The phosphate adsorptive properties of aluminum hydroxides and related compounds have been investigated extensively by many authors from an environmental or a geological standpoint. The reaction of aluminum hydroxide with phosphate in the aqueous phase belongs to the adsorption-precipitation boundary system.…”

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A Kinetic Study of Phosphate Adsorption by Boehmite

Tang

Shima²,

Ookubo³

et al. 1997

Journal of Pharmaceutical Sciences

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Rates of phosphate adsorption to PT-A (a new type of aluminium oxide hydroxide) and ALG (aluminum hydroxide gel) from a pH 3 phosphate solution were measured by a batch method. Phosphate uptake progressed mainly by the adsorption mechanism for PT-A, but dissolution of aluminum and precipitation of aluminum phosphate took place in addition to phosphate adsorption for ALG. The intraparticle diffusivities (Dp'S) of phosphate were evaluated from the time courses of adsorption using the model of pore diffusion with a Freundlich-type adsorption isotherm. The Dp values were approximately 7 x 10(-7) cm2 S-1 for PT-A and 1 x 10(-6) cm2 s(-1) for ALG. The tortuosity factors calculated from a model of parallel plate pore were 5.1 for PT-A and 6.7 for ALG; these values resembled those for porous inorganic ion exchangers. The adsorption rates are high enough for each of the samples to be utilized as a phosphate adsorbent to prevent hyperphosphatemia in patients on chronic dialysis. PT-A is favored as a phosphate adsorbent because of its high chemical stability against acid.

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“…Οι παραπάνω προσροφητές δεν είναι οι μόνοι που χρησιμοποιούνται. Δομές της μορφής AlO(OH) nH 2 O (0 ≤ n < 1) με την γενικότερη ονομασία υροξείδια του αργιλίου έχουν χρησιμοποιηθεί στην αιμοδιάλυση για την προσρόφηση φοσφωρικών αλάτων στο αίμα [50][51].…”

Section: εφαρμογές των προσροφητώνunclassified

Συμπολυμερή Της Βινυλοπυρρολιδόνης Ως Αντίδοτα Εξωγενών Ουσιών

Αλεγκάκης¹

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Επιστημονικός συνεργάτης στο πρόγραμμα «Νέα πολυμερικα υλικά ελεγχόμενης απόδοσης με ανοσοενεργό δράση» σε συνεργασία με το Εργαστήριο Φυσικοχημικών Ερευνών (Καθ. Απόστολος Ρίζος). Διδακτική Εμπειρία ◊ Εισαγωγή στο λειτουργικό σύστημα Unix. Εισαγωγή στη γλώσσα προγραμματισμού FORTRAN. Σαρτζετάκης Νεκτάριος και Αλεγκάκης Αθανάσιος (επίβλεψη Γιώργος Βιτσάκης). Κέντρο Πανεπιστήμιο Κρήτης (1995). (Εισαγωγή στο γλώσσα προγραμματισμού FORTRAN, το λειτουργικό σύστημα UNIX, γραφικά πακέτα και εφαρμογές). ◊ Διδασκαλία Υπολογιστών στα Γυμνάσια Τυμπακίου και Αγίων Δέκα Νομού Ηρακλείου (Ιανουάριος '96 -Ιούνιος '96). ◊ Παρακολούθηση μαθημάτων για καταγραφή και επιδημιολογία καρκίνου «Cancer registry and Epidemiology» του European School of Oncology. Διοργάνωση: Ίδρυμα Εγνατία, Μέτσοβο, Οκτώβριος 1996. Σελίδα-viii-◊ Διδασκαλία υπολογιστών σε δασκάλους στα πλαίσια προγράμματος εξομοίωσης (Σεπτέμβριος 98 -Μαίος 99). ◊ Βοηθός μαθημάτων «Βιοστατιστικής» και «Ιατρικής Πληροφορικής» στο Ιατρικό Τμήμα Πανεπιστημίου Κρήτης (1997-σήμερα). Επιστημονικά Ενδιαφέροντα ⇒ Στατιστική ανάλυση καρκίνου στην Κρήτη και τροχαίων ατυχημάτων στην Κρήτη. ⇒ Υπολογιστικά μοντέλα προσομοίωσης φυσικοχημικών ιδιοτήτων. ⇒ Μαθηματικά μοντέλα και ιατρικές χρήσεις. ⇒ Πολυμερικά υλικά και φυσικοχημικές ιδιότητες. Φυσικοχημική και μαθηματική ανάλυση ιδιοτήτων. ⇒ Μυκοτοξίνες: Ανίχνευση και προφύλαξη. ⇒ Φαρμακοκινητικά μοντέλα αντιβιοτικών (π.χ. κεφτριαξόνη, λιδοκαίνη) ⇒ Γνώση αναλυτικών τεχνικών (HPLC, GC).

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Mechanism of Phosphate Adsorption to a Three-Dimensional Structure of Boehmite in the Presence of Bovine Serum Albumin

Cited by 6 publications

References 21 publications

Impedimetric method to monitor biological layer formation on central venous catheters for hemodialysis made of carbothane

Impedimetric method to monitor biological layer formation on central venous catheters for hemodialysis made of carbothane

A Kinetic Study of Phosphate Adsorption by Boehmite

Συμπολυμερή Της Βινυλοπυρρολιδόνης Ως Αντίδοτα Εξωγενών Ουσιών

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