Mechanism of Toona sinensis-stimulated adrenal steroidogenesis in primary rat adrenal cells

Chen, Yung Chia; Liang, Yi Lin; Huang, Yuan; Huang, Bu Miin

doi:10.1016/j.jff.2015.02.012

Cited by 5 publications

(2 citation statements)

References 17 publications

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“…Roem (Meliaceae), a perennial deciduous arbour, is widely distributed in eastern Asia (Edmonds & Staniforth, 1998). The leaves of T. sinensis, which contain a distinct flavour, are very popular in vegetarian cuisine and have long been used as a nutritious food in China and Malaysia and as animal fodder in India (Chen, Liang, Huang, & Huang, 2015). Almost every part of T. sinensis, including seeds, bark, root bark, petioles, and especially leaves, has a medicinal effect (Chang et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Limonoids isolated from Toona sinensis and their radical scavenging, anti-inflammatory and cytotoxic activities

Song

Mao

et al. 2016

Journal of Functional Foods

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A B S T R A C TA phytochemical investigation of the ethanol extract of Toona sinensis (A. Juss.) Roem resulted in the isolation of ten new limonoids, toonasinenines A-J (1-10), together with two known compounds, toonafolin (11) and toonacilianin D (12). Their structures were determined by spectroscopic analyses. The isolated components were evaluated in vitro for radical scavenging potential using ABTS ·+ and DPPH test, anti-inflammatory activities for Cox-1 and Cox-2, and cytotoxicies against nine tumour cell lines (A549, BGC-823, CHG-5, HCT15, HeLa, HepG2, MDA-MB-231, SHG-44 and SGC-7901 cells). As a result, 4, 5 and 7-10 showed potent radical scavenging activities, while limonoids 1-4 and 11 exhibited significant antiinflammatory and cytotoxic potential.

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Section: Introductionmentioning

confidence: 99%

Limonoids isolated from Toona sinensis and their radical scavenging, anti-inflammatory and cytotoxic activities

Song

Mao

et al. 2016

Journal of Functional Foods

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“…The leaves of T. sinensis , which contain a distinct flavor, are very popular in vegetarian cuisine and have long been used as a nutritious food in China and Malaysia [2]. In folk, almost every part of T. sinensis , including seeds, bark, root bark, petioles, and leaves, can be used to treat cold, rheumatic pain, stomach pain, and diarrhea without any irreversible side effects [3, 4].…”

Section: Introductionmentioning

confidence: 99%

Lactam Triterpenoids from the Bark of Toona sinensis

Meng

Peng

et al. 2016

Nat. Prod. Bioprospect.

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Three new limonoid-type triterpenoids, namely toonasins A–C (1–3) with a rare lactam E ring, along with six known compounds (4–9) were isolated from the barks of Toona sinensis. The structures of new compounds were elucidated by interpretation of spectroscopic data, and the relative configuration of compound 1 was further characterized by X-ray crystallographic analyses. The isolated compounds were evaluated for their cytotoxic activities against five human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7 and SW480), and compounds 3 and 5 showed weak cytotoxicities.Electronic supplementary materialThe online version of this article (doi:10.1007/s13659-016-0108-4) contains supplementary material, which is available to authorized users.

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Toonasindiynes A-F, new polyacetylenes from Toona sinensis with cytotoxic and anti-inflammatory activities

Zhou

et al. 2020

Fitoterapia

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Mechanism of Toona sinensis-stimulated adrenal steroidogenesis in primary rat adrenal cells

Cited by 5 publications

References 17 publications

Limonoids isolated from Toona sinensis and their radical scavenging, anti-inflammatory and cytotoxic activities

Limonoids isolated from Toona sinensis and their radical scavenging, anti-inflammatory and cytotoxic activities

Lactam Triterpenoids from the Bark of Toona sinensis

Toonasindiynes A-F, new polyacetylenes from Toona sinensis with cytotoxic and anti-inflammatory activities

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