Mechanisms involved in the conduction of anterior temporal epileptiform discharges to the scalp

Sparkes, Matthew; Valentin, Antonio; Alarcón, Gonzalo

doi:10.1016/j.clinph.2009.08.026

Cited by 25 publications

(16 citation statements)

References 14 publications

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“…As early as 1960 (Silverman 1960) and 1980's (Binnie et al, 1982;, it was pointed out that the 10-20 system did not cover the inferior-basal part of the temporal lobes. This was further supported by studies using anterior temporal electrodes T1-T2 Homan et al, 1988;Mintzer et al, 2002;Sperling and Engel, 1985), Maudsley T1'T2' electrodes (Corsini et al, 2006;Nayak et al, 2004) or multiple nonstandard electrode positions (Gelisse et al, 2011;Kissani et al, 2001;Ochoa et al, 2008;Sadler and Goodwin, 1989;Sirin et al, 2013;Sparkes et al, 2009;Yamazaki et al, 2012;Zijlmans et al, 2008).…”

Section: Introductionmentioning

confidence: 82%

Added clinical value of the inferior temporal EEG electrode chain

Justesen¹,

Johansen²,

Martinussen³

et al. 2018

Clinical Neurophysiology

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Section: Introductionmentioning

confidence: 82%

Added clinical value of the inferior temporal EEG electrode chain

Justesen¹,

Johansen²,

Martinussen³

et al. 2018

Clinical Neurophysiology

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“…In addition to electrode montage, head model, and time points of interictal spike, recent studies have suggested that skull holes may also have impact on EEG source localization (Heasman et al, 2002; Sparkes et al, 2009). Sparkes et al (2009) reported that skull holes play a role in the transmission to the scalp of epileptiform discharges and they suggested that facial and anterior temporal electrodes should be used to acquire EEG signals for localizing the epileptogenic sources in temporal lobe epilepsy.…”

Section: Discussionmentioning

confidence: 99%

“…Sparkes et al (2009) reported that skull holes play a role in the transmission to the scalp of epileptiform discharges and they suggested that facial and anterior temporal electrodes should be used to acquire EEG signals for localizing the epileptogenic sources in temporal lobe epilepsy. The effect of skull holes to EEG source localization remains to be further studied.…”

Section: Discussionmentioning

confidence: 99%

Interictal spike analysis of high-density EEG in patients with partial epilepsy

Wang

Worrell

Yang

et al. 2011

Clinical Neurophysiology

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Objective The aim of this study is to investigate the use of interictal spikes to localize epileptogenic brain from noninvasive scalp EEG recordings in patients with medically intractable epilepsy. Methods Source reconstructions were performed using a high density electrode montage and a low density electrode montage by means of a distributed source modeling method. The source of interictal spike activity was localized using both realistic geometry boundary element method (BEM) head models and the 3-shell spherical head model. Results In the analysis of 7 patients, the high density electrode montage was found to provide results more consistent with the suspected region of epileptogenic brain identified for surgical resection using intracranial EEG recordings and structural MRI lesions, as compared to the spatial low density electrode montage used in routine clinical practice. Furthermore, the realistic geometry BEM head model provided better source localization. Conclusions Our results indicate the merits of using high density scalp EEG recordings and realistic geometry head modeling for source localization of interictal spikes in patients with partial epilepsy. Significance The present results suggest further improvement of source localization accuracy of epileptogenic brain from interictal EEG recorded using high density scalp electrode montage and realistic geometry head models.

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“…Blood vessels not only permeate the skull diploe but, at specific locations, directly pierce through the skull bone. As in the case of nerve foramina and surgical skull holes (Chauveau et al, 2004; Lanfer et al, 2012a; van den Broek et al, 1998; Heasman et al., 2002; Bénar and Gotman, 2002; Li et al, 2007; Oostenveld and Oostendorp, 2002; Sparkes et al, 2009; Thevenet et al, 1992; Vanrumste et al, 2000), these direct connections (foramina) between brain and head surface may significantly influence the forward and inverse propagation of electrical fields. However, the impact of these skull foramina due to blood vessels on VCHMs has thus far not been addressed.…”

Section: Introductionmentioning

confidence: 99%

The role of blood vessels in high-resolution volume conductor head modeling of EEG

et al. 2016

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Reconstruction of the electrical sources of human EEG activity at high spatiotemporal accuracy is an important aim in neuroscience and neurological diagnostics. Over the last decades, numerous studies have demonstrated that realistic modeling of head anatomy improves the accuracy of source reconstruction of EEG signals. For example, including a cerebrospinal fluid compartment and the anisotropy of white matter electrical conductivity were both shown to significantly reduce modeling errors. Here, we for the first time quantify the role of detailed reconstructions of the cerebral blood vessels in volume conductor head modeling for EEG. To study the role of the highly arborized cerebral blood vessels, we created a submillimeter head model based on ultra-high-field-strength (7 T) structural MRI datasets. Blood vessels (arteries and emissary/intraosseous veins) were segmented using Frangi multi-scale vesselness filtering. The final head model consisted of a geometry-adapted cubic mesh with over 17 × 106 nodes. We solved the forward model using a finite-element-method (FEM) transfer matrix approach, which allowed reducing computation times substantially and quantified the importance of the blood vessel compartment by computing forward and inverse errors resulting from ignoring the blood vessels. Our results show that ignoring emissary veins piercing the skull leads to focal localization errors of approx. 5 to 15 mm. Large errors (>2 cm) were observed due to the carotid arteries and the dense arterial vasculature in areas such as in the insula or in the medial temporal lobe. Thus, in such predisposed areas, errors caused by neglecting blood vessels can reach similar magnitudes as those previously reported for neglecting white matter anisotropy, the CSF or the dura — structures which are generally considered important components of realistic EEG head models. Our findings thus imply that including a realistic blood vessel compartment in EEG head models will be helpful to improve the accuracy of EEG source analyses particularly when high accuracies in brain areas with dense vasculature are required.

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Mechanisms involved in the conduction of anterior temporal epileptiform discharges to the scalp

Cited by 25 publications

References 14 publications

Added clinical value of the inferior temporal EEG electrode chain

Added clinical value of the inferior temporal EEG electrode chain

Interictal spike analysis of high-density EEG in patients with partial epilepsy

The role of blood vessels in high-resolution volume conductor head modeling of EEG

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