2024
DOI: 10.1016/j.theriogenology.2023.12.027
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Mechanisms of LPS–induced epithelial mesenchymal transition in bEECs

Mingkun Sun,
Pengjie Song,
Yu Zhao
et al.
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“…EMT is abnormally activated in human cancers, providing a special capacity for tumor cell movement that contributes to tumor cell invasion 42 . Some evidence indicates that the TLR4/Myd88/NF-κB signaling pathway, as well as inflammatory cytokines, influenced the EMT process 43 46 . We performed in vivo and in vitro experiments to further validate the effect of LPS on the EMT process in esophageal cancer and revealed the accelerated EMT process progression in ESCC, which provides invasive and migratory properties to cancer cells.…”
Section: Discussionmentioning
confidence: 99%
“…EMT is abnormally activated in human cancers, providing a special capacity for tumor cell movement that contributes to tumor cell invasion 42 . Some evidence indicates that the TLR4/Myd88/NF-κB signaling pathway, as well as inflammatory cytokines, influenced the EMT process 43 46 . We performed in vivo and in vitro experiments to further validate the effect of LPS on the EMT process in esophageal cancer and revealed the accelerated EMT process progression in ESCC, which provides invasive and migratory properties to cancer cells.…”
Section: Discussionmentioning
confidence: 99%