Mechanisms of Napelline Action Stimulating the Regeneration of Hemopoietic Tissue in Cytostatic Myelosuppression

Zyuz’kov, G. N.; Zhdanov, V. V.; Удут, Е. В.; Мирошниченко, Л. А.; Losev, Evgeniy A.; Симанина, Е. В.; Chaikovskiy, A. V.; Суслов, Н. И.; Povet’eva, T. N.; Krapivin, A. V.; Nesterova, Yu. V.; Агафонов, В. И.; Minakova, M. Yu.; Ставрова, Л. А.; Данилец, М. Г.; Ligacheva, A. A.; Trofimova, E. S.; Ivanova, Alexandra N.; Goldberg, V. Е.; Reikchart, D. V.; Дыгай, А. М.

doi:10.1007/s10517-013-2172-7

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Cited by 6 publications

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“…Activation of functions of hemopoietic progenitor cells along with increased feeder capacity of the stromal elements in the hemopoiesis-inducing microenvironment with decreased levels mesenchymal progenitor cells in the bone marrow is the mechanisms underlying the hemostimulating action of napelline of A. baicalense (Zyuz'kov et al, 2013).…”

Section: Other Effectsmentioning

confidence: 99%

Chemical and biological studies of Aconitum pharmaceutical resources

Hao¹,

Gu²,

Xiao³

2015

Medicinal Plants

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Section: Other Effectsmentioning

confidence: 99%

Chemical and biological studies of Aconitum pharmaceutical resources

Hao¹,

Gu²,

Xiao³

2015

Medicinal Plants

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Cerebroprotective and Regenerative Effects of Alkaloid Z77 under Conditions of Brain Ischemia

et al. 2015

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We studied the psychopharmacological effects of atisine-type diterpene alkaloid Z77 in a rat model of cerebral ischemia. Pronounced cerebroprotective effect was found consisting in normalization of the orienting and exploratory activity and conditioned behavior associated with significant correction of morphological changes in the brain. The direct stimulatory effect of Z77 on neural stem cells was shown in vitro.

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Role of JNK and Contribution of p53 to the Realization of the Growth Potential of Mesenchymal Precursor Cells under the Effect of Fibroblast Growth Factor

et al. 2015

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The role of JNK-mediated signal pathway and participation of p53 transcription factor in stimulation of mesenchymal precursor cell function by the fibroblast growth factor was studied. The levels of fibroblast colony- and cluster formation and proliferative activity of mesenchymal precursors increased in response to JNK and p53 specific inhibitors. JNK and p53 blockers did not change the rate of fibroblast growth factor-induced progenitor element differentiation.

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Mechanisms of Napelline Action Stimulating the Regeneration of Hemopoietic Tissue in Cytostatic Myelosuppression

Cited by 6 publications

References 8 publications

Chemical and biological studies of Aconitum pharmaceutical resources

Chemical and biological studies of Aconitum pharmaceutical resources

Cerebroprotective and Regenerative Effects of Alkaloid Z77 under Conditions of Brain Ischemia

Role of JNK and Contribution of p53 to the Realization of the Growth Potential of Mesenchymal Precursor Cells under the Effect of Fibroblast Growth Factor

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