Based on government statistical data ~80% of the local Kamchatkan population (~250 ka people) live in the major cities on the coastal line of Avacha Gulf . It is the main transport seaway to Kamchatka , and and important Asia - North America air transport corridor. The Avacha Gulf is located in the Malko-Petropavlovsk zone of transverse dislocations (MPZ) on the extension of deep transform fault on the boundary between various ly aged slabs. Most of monogenetic cinder cones chaotic distributed in relation to the trench and belong to the long-living rupture zones of MPZ. Some of the monogenetic volcanoes are parasitic cones on the slopes of Koryaksky and Avachinsky stratovolcanoes and related with their magma plumbing systems. We here present new results of the geochemical and isotopic stud ies of monogenetic volcanism in MPZ. Based on whole rock and trace element geochemistry, Sr-Nd-Pb isotopic ratios of monogenetic volcanism, magmas were shown to sample the enriched mantle source with dominance decompression melting without significant inputs of the slab`s components. Calculations of the P, T conditions suggest magma residence of monogenetic cinder cones on the Moho boundary. That correlates with the geophysical observation of crustal discontinuity under the MPZ. Monogenetic cinder cones have an active magma plumbing system because during the Holocene time were several periods of activations. Presented results show necessary install continuous monitoring of environment changing around the Avacha Gulf and more serious attention from government and science. A more detailed investigation of MPZ will help degrease potential risks of eruptions from monogenetic volcanoes for human and infrastructures.