Mechanisms of Quality of Life and Social Support in Inflammatory Bowel Disease

Katz, Laura; Tripp, Dean A.; Ropeleski, Mark J.; Depew, William T.; Nickel, J. Curtis; Vanner, Stephen; Beyak, Michael

doi:10.1007/s10880-015-9431-x

Cited by 29 publications

(14 citation statements)

References 58 publications

(91 reference statements)

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“…This study did not include a comparator disease group as there are no comparable comprehensive liver disease patient cohorts. However, work in inflammatory bowel disease (IBD) found that diminished IBD‐quality of life was predicted by younger age and social interaction variables were associated with IBD‐quality of life . In contrast, fatigue associated with renal transplantation has a greater symptomatic impact in older patients …”

Section: Discussionmentioning

confidence: 99%

The inter‐relationship of symptom severity and quality of life in 2055 patients with primary biliary cholangitis

Dyson

Wilkinson

Jopson

et al. 2016

Aliment Pharmacol Ther

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SummaryBackgroundAge at presentation with primary biliary cholangitis (PBC) is associated with differential response to ursodeoxycholic acid (UDCA) therapy. Younger‐presenting patients are less likely to respond to treatment and more likely to need transplant or die from the disease. PBC has a complex impact on quality of life (QoL), with systemic symptoms often having significant impact.AimTo explain the impact of age at presentation on perceived QoL and the inter‐related symptoms which impact upon it.MethodsUsing the UK‐PBC cohort, symptoms were assessed using the PBC‐40 and other validated tools. Data were available on 2055 patients.ResultsOf the 1990 patients reporting a global PBC‐QoL score, 66% reported good/neutral scores and 34% reported poor scores. Each 10‐year increase in age at presentation was associated with a 14% decrease in risk of poor perceived QoL (OR = 0.86, 95% CI: 0.75–0.98, P < 0.05). All symptom domains were similarly age‐associated (P < 0.01). Social dysfunction was the symptom factor with the greatest impact on QoL. Median (interquartile range) PBC‐40 social scores for patients with good perceived QoL were 18 (14–23) compared with 34 (29–39) for those with poor QoL.ConclusionThe majority of patients with primary biliary cholangitis do not feel their QoL is impaired, although impairment is reported by a sizeable minority. Age at presentation is associated with impact on perceived QoL and the symptoms impairing it, with younger patients being more affected. Social dysfunction makes the greatest contribution to QoL impairment, and it should be targeted in trials aimed at improving life quality.

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Section: Discussionmentioning

confidence: 99%

The inter‐relationship of symptom severity and quality of life in 2055 patients with primary biliary cholangitis

Dyson

Wilkinson

Jopson

et al. 2016

Aliment Pharmacol Ther

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“…Social support, referred to as the support from family, friends and others, is identified as a protective factors for increased HRQoL across a variety of chronic diseases [24]. It was found that high levels of social support could help minimize pain and stress, provide a buffer against psychological distress, and enhance self-management [24]. Empirical studies have shown that IBD patients with lower perceived support had an impairment of HRQoL [13,24].…”

Section: Introductionmentioning

confidence: 99%

“…It was found that high levels of social support could help minimize pain and stress, provide a buffer against psychological distress, and enhance self-management [24]. Empirical studies have shown that IBD patients with lower perceived support had an impairment of HRQoL [13,24]. However, literatures on the relationships between social support and IBD-related HRQoL were relatively lacking.…”

Section: Introductionmentioning

confidence: 99%

Associations between disease activity, social support and health-related quality of life in patients with inflammatory bowel diseases: the mediating role of psychological symptoms

Kaminga

Peng

et al. 2020

BMC Gastroenterol

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Background: Previous studies have indicated that disease activity, psychological symptoms and social support were associated with health-related quality of life (HRQoL) in patients with inflammatory bowel diseases(IBD). However, it is unclear how disease activity, psychological symptoms and social support interact to affect HRQoL. The main purpose of this study was to examine the mediation effect of psychological symptoms in the relationship between disease activity, social support and HRQoL. Methods: This was a cross-sectional study, which collected data using convenience sampling, between December 2016 and March 2018, from the Third XiangyaHospital of Central South University in Changsha, China. An online self-administered questionnaire (including demographic and clinical information), Inflammatory Bowel Disease Questionnaire, Disease Activity Indices scale, Hospital Anxiety and Depression Scale and Social Support Rating Scale, were administered to each participant. Descriptive statistics and Pearson's correlations were used to summarize data, whereas PROCESS analysis was performed to examine the pre-specified mediation effect. Results: A total of 199 patients with IBD were included. Disease activity indices (DAI) and hospital anxiety and depression (HAD) were negatively correlated with HRQoL (β = − 3.37, − 2.54 respectively, P < 0.001), while social support was positively correlated with HRQoL (β = 1.38, P < 0.01). HAD partially mediated the negative relationship between DAI and HRQoL (β = − 0.83, P < 0.001) with the mediation effect ratio of 24.6%, and completely mediated the positive relationship between social support and HRQoL (β = 1.20, P < 0.001). Conclusions: Psychological symptoms acted as a mediator in the relationship between disease activity, social support and HRQoL. Interventions to improve HRQoL in patients with IBD should take into account the mediation effect of psychological symptoms.

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“…This points to the significant role played by support networks in the lives of patients -on one hand, emotional support can help patients in everyday life, and on the other -the strength of the symptoms is strongly associated with the need for support. The described relationships were also The sense of coherence, social support and quality of life among patients with inflammatory bowel disease examined in other studies -it has been proven that the support provided by family, friends and others is significantly related to the quality of life of IBD patients [25]. Other studies have shown that perceived social support is a predictor of quality of life in patients with Crohn's disease and ulcerative colitis [23].…”

Section: Discussionmentioning

confidence: 89%

The sense of coherence, social support and quality of life among patients with inflammatory bowel disease

Bieńkowski

Rudnik

Bidzan

2019

Pomeranian Journal of Life Sciences

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Introduction: Inflammatory bowel disease (IBD) is a group of chronic digestive system conditions which significantly influence the everyday life of patients. Exhausting intestinal discomfort might cause a strong feeling of distress and lowers the quality of life. This study was based on the question: how are the sense of coherence, social support, socio-demographic variables and the duration of disease related to the quality of life of individuals suffering from IBD?Materials and methods: Thirty-nine individuals suffering from IBD were examined: 21 with ulcerative colitis, 17 with Crohn’s disease and 1 with microscopic colitis. The participants completed a socio-demographic survey, and Life Orientation Questionnaire (SOC-29) and Berlin Social Support Scales (BSSS) questionnaires. The quality of life was examined by the Functional Assessment of Cancer Therapy-Gastric (FACT-Ga) questionnaire.Results: The overall rate of the sense of coherence with its components and the available instrumental and emotional support was found to be significantly connected to the patients’ quality of life. The level of education differentiated the examined patients in terms of the quality of life.Conclusions: Psychological resources can play a significant role in the assessment of the impact of chronic disease on patients’ everyday life. It is important to focus on their importance in raising the quality of life of the patients.

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Mechanisms of Quality of Life and Social Support in Inflammatory Bowel Disease

Cited by 29 publications

References 58 publications

The inter‐relationship of symptom severity and quality of life in 2055 patients with primary biliary cholangitis

The inter‐relationship of symptom severity and quality of life in 2055 patients with primary biliary cholangitis

Associations between disease activity, social support and health-related quality of life in patients with inflammatory bowel diseases: the mediating role of psychological symptoms

The sense of coherence, social support and quality of life among patients with inflammatory bowel disease

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