Mechanisms of the Masquelet technique to promote bone defect repair and its influencing factors

Curcumin-loaded scaffolds in bone regeneration

“…After a designated interval of 6–8 weeks, the induced membrane is meticulously incised, the spacer extracted, and cancellous bone from the iliac crest implanted, with subsequent closure of the membrane utilizing primary fixation. Despite the promise of this method, attendant side effects necessitate thorough investigation and optimization of surgical protocols for its optimal utilization [ 31 ].…”