Mechanisms of wolfberry in the treatment of liver diseases

Che, Zhaodi; Zhou, Zheng-Qun; Xiao, Jia

doi:10.1360/tb-2020-1419

Cited by 1 publication

(1 citation statement)

References 22 publications

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“…The biological properties of wolfberries have been also largely reported and reviewed. For instance, when performing a browse search in the Web of Science platform in November 2022 using the following key words "Lycium barbarum review", and restricting for year 2022 only, it is possible to find a large number of review papers that have in their scope of analysis this species, as well as its antioxidant, anti-inflammatory, anti-aging, hypoglycemic and hypolipidemic activities, modulation of gut microbiota, neuroprotective, neuroprotective effects on retinal ganglion cells, immunomodulatory, positive effects on cognitive impairment, anti-fatigue effect, hepatoprotective, and anti-tumor effect [45][46][47][48][49][50][51][52][53][54][55][56][57][58][59][60][61][62]. The role of the plant polysaccharides, including that of L. barbarum, in drug delivery system in tumor treatment, targeted therapy, and wound healing was also reviewed and discussed [63].…”

Section: Introductionmentioning

confidence: 99%

Chemical and Biological Properties of Three Poorly Studied Species of Lycium Genus—Short Review

Miguel

2022

Metabolites

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The genus Lycium belongs to the Solanaceae family and comprises more than 90 species distributed by diverse continents. Lycium barbarum is by far the most studied and has been advertised as a “superfood” with healthy properties. In contrast, there are some Lycium species which have been poorly studied, although used by native populations. L. europaeum, L. intricatum and L. schweinfurthii, found particularly in the Mediterranean region, are examples of scarcely investigated species. The chemical composition and the biological properties of these species were reviewed. The biological properties of L. barbarum fruits are mainly attributed to polysaccharides, particularly complex glycoproteins with different compositions. Studies regarding these metabolites are practically absent in L. europaeum, L. intricatum and L. schweinfurthii. The metabolites isolated and identified belong mainly to polyphenols, fatty acids, polysaccharides, carotenoids, sterols, terpenoids, tocopherols, and alkaloids (L. europaeum); phenolic acids, lignans, flavonoids, polyketides, glycosides, terpenoids, tyramine derivatives among other few compounds (L. schweinfurthii), and esters of phenolic acids, glycosides, fatty acids, terpenoids/phytosterols, among other few compounds (L. intricatum). The biological properties (antioxidant, anti-inflammatory and cytotoxic against some cancer cell lines) found for these species were attributed to some metabolites belonging to those compound groups. Results of the study concluded that investigations concerning L. europaeum, L. intricatum and L. schweinfurthii are scarce, in contrast to L. barbarum.

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