Mechanisms underlying the supra-maximal thermogenesis elicited by aminophylline in rats

Wang, Lawrence C.H.; Jourdan, M.L.; Lee, T.F.

doi:10.1016/0024-3205(89)90491-8

Cited by 13 publications

(4 citation statements)

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“…Plasma concentrations of glucose and free fatty acids (FFAs) also increased, but insulin secretion was inhibited (14). Caffeine (15) and aminophylline also block adenosine receptors (16), which is an effect that may have a greater impact on metabolism than the inhibition of phosphodiesterase (17). The combined effects are expected to enhance lipolysis, glycogenolysis and gluconeogenesis and hence contribute to enhanced maximal thermogenesis (10).…”

Section: Discussionmentioning

confidence: 99%

Aminophylline Partially Prevents the Decrease of Body Temperature during Laparoscopic Abdominal Surgery

et al. 2014

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Aminophylline can elicit thermogenesis in rats or increase metabolic rate during cold stress in lambs. We tested the hypothesis that aminophylline would reduce the change in core body temperature during laparoscopic abdominal surgery requiring pneumoperitoneum. Fifty patients were randomly divided into an aminophylline group (n=25) and a saline control group (n=25). Esophageal temperature, index finger temperature, and hemodynamic variables, such as mean blood pressure and heart rate, were measured every 15 min during sevoflurane anesthesia. In the aminophylline group, esophageal temperatures at T45 (36.1±0.38 vs. 35.7±0.29, P=0.024), T60 (36.0±0.39 vs. 35.6±0.28, P=0.053), T75 (35.9±0.34 vs. 35.5±0.28, P=0.025), T90 (35.8±0.35 vs. 35.3±0.33, P=0.011), and T105 (35.8±0.36 vs. 35.1±0.53, P=0.017) and index finger temperatures at T15 (35.8±0.46 vs. 34.9±0.33, P<0.001), T30 (35.7±0.36 vs. 35.0±0.58, P=0.029), T45 (35.8±0.34 vs. 35.2±0.42, P=0.020), T60 (35.7±0.33 vs. 34.9±0.47, P=0.010), T75 (35.6±0.36 vs. 34.8±0.67, P=0.028), T90 (35.4±0.55 vs. 34.4±0.89, P=0.042), and T105 (34.9±0.53 vs. 33.9±0.85, P=0.024) were significantly higher than in the saline control group. Aminophylline is effective in maintaining the core temperature through a thermogenic effect, despite reduced peripheral thermoregulatory vasoconstriction.Graphical Abstract

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Section: Discussionmentioning

confidence: 99%

Aminophylline Partially Prevents the Decrease of Body Temperature during Laparoscopic Abdominal Surgery

et al. 2014

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“…The involvement of A 1 receptors in a variety of metabolic processes was described earlier. Furthermore, it was found that pretreatment with specific A 1 receptor antagonist significantly enhanced thermogenesis and improved resistance in rats under cold exposure 2,3,5 …”

Section: Discussionmentioning

confidence: 99%

“…As previous studies have revealed, adenosine agonists and antagonists indicate thermoregulatory action. For example, the agonists N 6 ‐cyclohexyladenosine (CHA) and 5′‐ N ‐ethylcarboxamidoadenosine (NECA) possess antipyretic activity, and antagonists, such as xanthine derivatives produce hyperthermia or enhance thermogenesis in animals exposed to cold 1–4 …”

Section: Introductionmentioning

confidence: 99%

The Effect of N⁶‐Cyclohexyladenosine and 5′‐(N‐Cyclopropyl)‐Carboxamidoadenosine on Pyrogen Fever in Rabbits

Gągało

Matuszek

1997

Annals of the New York Academy of Sciences

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“…The diverse way in which different court evaluate these variables will inevitably belie the degree of cohesion. 164 These include how to secure adequate information about foreign laws and how to interpret them proficiently. 165 (3).…”

Section: B New Uncertaintiesmentioning

confidence: 99%

Respectful Consideration, but Not Deference: Chinese Sovereign Amici in the US Supreme Court Vitamin C Judgment

2020

Journal of European Competition Law &Amp; Practice

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In the first lawsuit in the U.S. history, the Vitamin C witnesses the Chinese government's intervention to take a position as amicus curiae.• It is also for the first time, the U.S. Supreme Court has articulated a "respectful consideration" test that lower courts should use in the application of Federal Rule of Civil Procedure (FRCP) 44.1 while dealing with foreign sovereign's interpretation of their own law. • The implications of the Supreme Court's decision reach well beyond the confines of antitrust doctrine. In an era of increasing globalisation, the case sets the ground rules for a broad range of cross-border disputes.

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Mechanisms underlying the supra-maximal thermogenesis elicited by aminophylline in rats

Cited by 13 publications

References 20 publications

Aminophylline Partially Prevents the Decrease of Body Temperature during Laparoscopic Abdominal Surgery

Aminophylline Partially Prevents the Decrease of Body Temperature during Laparoscopic Abdominal Surgery

The Effect of N⁶‐Cyclohexyladenosine and 5′‐(N‐Cyclopropyl)‐Carboxamidoadenosine on Pyrogen Fever in Rabbits

Respectful Consideration, but Not Deference: Chinese Sovereign Amici in the US Supreme Court Vitamin C Judgment

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Mechanisms underlying the supra-maximal thermogenesis elicited by aminophylline in rats

Cited by 13 publications

References 20 publications

Aminophylline Partially Prevents the Decrease of Body Temperature during Laparoscopic Abdominal Surgery

Aminophylline Partially Prevents the Decrease of Body Temperature during Laparoscopic Abdominal Surgery

The Effect of N6‐Cyclohexyladenosine and 5′‐(N‐Cyclopropyl)‐Carboxamidoadenosine on Pyrogen Fever in Rabbits

Respectful Consideration, but Not Deference: Chinese Sovereign Amici in the US Supreme Court Vitamin C Judgment

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The Effect of N⁶‐Cyclohexyladenosine and 5′‐(N‐Cyclopropyl)‐Carboxamidoadenosine on Pyrogen Fever in Rabbits