Mechanistic Insight to Bioremediation of Hazardous Metals and Pesticides from Water Bodies by Microbes

Dey, Priyadarshini; Gola, Deepak; Chauhan, Nitin; Bharti, Randhir K.; Malik, Anushree

doi:10.1007/978-981-15-5901-3_23

Cited by 3 publications

(1 citation statement)

References 97 publications

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“…The conventional physico-chemical methods, such as chemical precipitation, ion exchange, adsorption, membrane filtration, coagulation-flocculation, and flotation, are usually utilized to remediate these harmful contaminants. These techniques have the disadvantages of being expensive, having low selectivity, production of additional sludge, and further treatment is required for better results ( Dey et al, 2021 ; Zamora-Ledezma et al, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

Insight Into the Molecular Mechanisms Underpinning the Mycoremediation of Multiple Metals by Proteomic Technique

et al. 2022

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We investigated the fungus Aspergillus fumigatus PD-18 responses when subjected to the multimetal combination (Total Cr, Cd2+, Cu2+, Ni2+, Pb2+, and Zn2+) in synthetic composite media. To understand how multimetal stress impacts fungal cells at the molecular level, the cellular response of A. fumigatus PD-18 to 30 mg/L multimetal stress (5 mg/L of each heavy metal) was determined by proteomics. The comparative fungal proteomics displayed the remarkable inherent intracellular and extracellular mechanism of metal resistance and tolerance potential of A. fumigatus PD-18. This study reported 2,238 proteins of which 434 proteins were exclusively expressed in multimetal extracts. The most predominant functional class expressed was for cellular processing and signaling. The type of proteins and the number of proteins that were upregulated due to various stress tolerance mechanisms were post-translational modification, protein turnover, and chaperones (42); translation, ribosomal structure, and biogenesis (60); and intracellular trafficking, secretion, and vesicular transport (18). In addition, free radical scavenging antioxidant proteins, such as superoxide dismutase, were upregulated upto 3.45-fold and transporter systems, such as protein transport (SEC31), upto 3.31-fold to combat the oxidative stress caused by the multiple metals. Also, protein–protein interaction network analysis revealed that cytochrome c oxidase and 60S ribosomal protein played key roles to detoxify the multimetal. To the best of our knowledge, this study of A. fumigatus PD-18 provides valuable insights toward the growing research in comprehending the metal microbe interactions in the presence of multimetal. This will facilitate in development of novel molecular markers for contaminant bioremediation.

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Section: Introductionmentioning

confidence: 99%

Insight Into the Molecular Mechanisms Underpinning the Mycoremediation of Multiple Metals by Proteomic Technique

et al. 2022

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Unveiling fungal strategies: Mycoremediation in multi-metal pesticide environment using proteomics

Dey,

Malik,

Singh

et al. 2024

Sci Rep

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Micropollutants, such as heavy metals and pesticides, inhibit microbial growth, threatening ecosystems. Yet, the mechanism behind mycoremediation of the pesticide lindane and multiple metals (Cd, Total Cr, Cu, Ni, Pb, Zn) remains poorly understood. In our study, we investigated cellular responses in Aspergillus fumigatus PD-18 using LC-MS/MS, identifying 2190 proteins, 1147 of which were consistently present under both stress conditions. Specifically, Cu-Zn superoxide dismutase and heat shock proteins were up-regulated to counter oxidative stress and protein misfolding. Proteins involved in intracellular trafficking, secretion, and vesicular transport; RNA processing and modification showed enhanced abundance and regulating stress response pathways. Additionally, haloalkane dehalogenase and homogentisate 1,2-dioxygenase played pivotal roles in lindane mineralization. Bioinformatics analysis highlighted enriched pathways such as Glyoxylate and dicarboxylate metabolism and Purine metabolism, that are crucial for combating adverse environments. We identified the hub protein 26 S proteasome regulatory subunit complex as potential biomarker and remedial targets for mycoremediation of wastewater, suggesting practical applications for environmental remediation.

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AI-Driven MCDM Tools for Optimizing Industrial Wastewater Treatment

Rana,

Bhambri

2024

Advances in Computer and Electrical Engineering

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This chapter describes the recent focus on electricity use in wastewater treatment plants (WWTPs), which has led to research to improve efficiency and identify energy savings, and explains how multiple decision-making methods (MCDM) can be used to treat wastewater Treatment. One cubic meter of wastewater requires at least 0.18 kWh of electricity to treat. Aeration accounts for approximately 50% of the energy required for the process, depending on the level of treatment and the size of the site. This section describes how to save energy in wastewater treatment plants, highlighting the transition from traditional management to artificial intelligence (AI)-based technology. This section highlights the importance of wastewater treatment. It presents a comprehensive review of the literature over the last decade. It aims to contribute to the ongoing discussion on improving the efficiency and sustainability of wastewater treatment plants. It includes traditional management and technology, focusing on intelligence-based management using algorithms such as neural networks and fuzzy logic.

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Mechanistic Insight to Bioremediation of Hazardous Metals and Pesticides from Water Bodies by Microbes

Cited by 3 publications

References 97 publications

Insight Into the Molecular Mechanisms Underpinning the Mycoremediation of Multiple Metals by Proteomic Technique

Insight Into the Molecular Mechanisms Underpinning the Mycoremediation of Multiple Metals by Proteomic Technique

Unveiling fungal strategies: Mycoremediation in multi-metal pesticide environment using proteomics

AI-Driven MCDM Tools for Optimizing Industrial Wastewater Treatment

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