Mechanistic, participant, and movement-related factors that contribute to low-flow-mediated constriction

The Role of Human and Animal Monocytes and Macrophages in Homeostasis and Disease

“…These results indicate that marine invertebrates could be an attractive source of novel antimicrobial agents. Using Drosophila's innate immune system as a model for antiviral responses, Tramell et al [11] studied the insulin-mediated signaling regulation of the mosquito-borne West Nile virus. They identified peptide endothelin signaling as a novel pathway for West Nile infection and demonstrated its applicability to the human immune system.…”

“…They identified peptide endothelin signaling as a novel pathway for West Nile infection and demonstrated its applicability to the human immune system. These findings are highly significant as mosquito-borne arboviruses represent a significant threat to humans worldwide; they are also surprising because endothelins are vasoconstrictors, and thus regulate blood flow [11]. However, peptide endothelin signaling may have many other functions, such as the recently discovered regulation of sex differences in salt balance management and the kidney response to high salt intake [12].…”