2024
DOI: 10.14715/cmb/2024.70.4.41
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Mechanistic role of pyroptosis in tumor microenvironment and tumor immunotherapy

Rukset Attar,
Muhammad Zahid Qureshi,
Uteuliyev Yerzhan Sabitaliyevich
et al.

Abstract: In recent decades, extraordinary attention has been devoted to cell death pathways principally because of multifaceted regulatory roles in normal developmental and pathophysiological processes. The removal of functionally defective, infected or potentially malignant cells is regulated by programmed cell death (PCD) cascades. Pyroptotic cell death is a highly complicated pro-inflammatory form of cell death. Pyroptosis is characterized by the formation of pores in the plasma membrane by oligomerization of the N-… Show more

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