Mechanochemical Synthesis of Substituted 4H-3,1-Benzoxazin-4-ones, 2-Aminobenzoxazin-4-ones, and 2-Amino-4H-3,1-benzothiazin-4-ones Mediated by 2,4,6-Trichloro-1,3,5-triazine and Triphenylphosphine

Temperature‐Controlled Base‐Promoted Cyclization for the Synthesis of 2‐Amino‐4H‐benzo[d][1,3]thiazin‐4‐ones and 2‐Thioxo‐4(3H)‐quinazolinones

“…Various methods have been reported for the synthesis of both 2‐thioxo‐2,3‐dihydroquinazolin‐4(1 H )‐ones and 2‐amino‐4 H ‐benzo[ d ][1,3]thiazin‐4‐ones . In general, these valuable frameworks are synthesized from anthranilic acid derivatives and isothiocyanates under harsh conditions.…”

TBHP-promoted multicomponent reaction to access 2-aminobenzoxazinones using sodium chlorodifluoroacetate as the C1 synthon

“…6,7 The introduction of one carbon atom at the 2- or 4-position is crucial for constructing the benzoxazinone ring. 8–10 For example, in 2009, Booker-Milburn's group reported an appealing Pd-mediated carbonylation of N -arylureas through C–H activation/carbon monoxide insertion sequences (Scheme 1a). 8 a Sawant and co-workers illustrated the efficient synthesis of 2-aminobenzoxazinones via Pd-catalyzed tandem cross-coupling/cyclization between 2-azidobenzoic acids and isocyanides (Scheme 1b).…”