2023
DOI: 10.1002/mabi.202300122
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Mechanomorphological Guidance of Colloidal Gel Regulates Cell Morphogenesis

Abstract: Microstructural morphology of the extracellular matrix guides the organization of cells in 3D. However, current biomaterials‐based matrices cannot provide distinct spatial cues through their microstructural morphology due to design constraints. To address this, colloidal gels are developed as 3D matrices with distinct microstructure by aggregating ionic polyurethane colloids via electrostatic screening. Due to the defined orientation of interconnected particles, positively charged colloids form extended strand… Show more

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