Meconium-Stained Amniotic Fluid Across Gestation and Neonatal Acid-Base Status

Abstract

The rising incidence of meconium-stained amniotic fluid with gestational age is consistent with the hypothesis that fetal maturation is a major etiologic factor in meconium passage. Also, the lack of variation of mean umbilical arterial pH across gestation suggests that fetal acidemia is not increased when meconium passage occurs earlier in pregnancy rather than at later gestational ages.

Fetal outcome in deliveries with meconium stained liquor

“…Gupta et al 2 found significant increased rate (86.7%) of meconium in amniotic fluid after 37 weeks. Oyelese Y et al 3 also proposed similar findings. Present study shows birth weight of 2.6-3 kg in majority of patients.…”

Maternal and perinatal outcome in meconium stained amniotic fluid at term: a case control study

“…Most workers showed there is an association with fetal heart rate abnormalities, low Apgar scores and low arterial cord PH in the presence of meconium stained amniotic fluid. 1 The present study was undertaken to evaluate the significance of meconium stained amniotic fluid and its fetal outcome inparturients admitted to Mahatma Gandhi Medical College and Research Institute between January 2014 to June 2015.…”

“…Presence of meconium in the amniotic fluid has long been considered as ominous sign for fetal distress, although the exact cause is not known, passage of meconium is considered as physiological maturity of fetus. 1,2 Meconium reduces the antibacterial property of amniotic fluid by altering the level of zinc in it which leads to intra amniotic infections. In case of hypoxia, gasping of fetus results in meconium aspiration which neutralizes the surfactant action and promotes inflammation of lung tissues, whereas persistent hypoxia after birth, aspirated meconium results in pulmonary vascular and pulmonary hypertension.…”

“…However a significant association has been reported between the consistency of meconium and abnormal FHR patterns, increased rate of caesarean section and low Apgar scores. 1,5 Although the direct and indirect effects of meconium staining remain uncertain, MSAF is considered as a predictor of maternal and perinatal morbidity and mortality. 2 The present study was carried out to find out the maternal and perinatal outcome associated with meconium stained liquor in our institution.…”

Surveillance du travail dans les situations à risque

“…Un liquide amniotique méconial est constaté dans 10 à 20 % des accouchements [108,109]. Sa fréquence est en augmentation à partir de 39 SA [110].…”