“…Lipomas located in the mediastinum are uncommon Lipomatosis is a diffuse overgrowth of adipose tissue that can occur following steroid therapy. 39 Other benign adipocytic tumors, including lipoblastoma, 40 lipoblastomatosis, 41 hibernoma, 42 angiolipoma, 43 chondrolipoma, 44 spindle cell lipoma, 45 myelolipoma, 46 and atypical spindle cell/pleomorphic lipomatous tumor (ASPLT), 47 can arise in the mediastinum. In the 2020 World Health Organization (WHO) classification of soft tissue tumors, ASPLT is a newly described tumor under the adipocytic tumors category, 48 while angiomyolipoma has been reclassified under tumors of uncertain differentiation.…”