Mediastinal Masses: Retrospective Single Center Based Study

Baram, Aram; Tayeb, Zirak Anwar

doi:10.4172/1948-5956.1000422

Cited by 7 publications

(7 citation statements)

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“…In this study dyspnoea was the most commonly presenting symptom, which was in concordance with Baram and Tayeb [2] in a study of 85 patients, in which they found that dyspnoea alone was the main presenting symptom in 33 (38.82%) cases. In the present study of 60 cases, 21 benign and 39 malignant cases correlated with histopathological examination (Table 5).…”

Section: Discussionsupporting

confidence: 91%

Diagnostic accuracy of multidetector computed tomography scan in mediastinal masses assuming histopathological findings as gold standard

Pandey¹,

Jaipal²,

Mannan³

et al. 2018

Pol J Radiol

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PurposeAim of the study was to: 1) present MDCT characteristics of different mediastinal mass lesions, 2) estimate proportion of benign and malignant mediastinal mass lesions based on MDCT findings, and 3) find out the diagnostic accuracy with sensitivity, specificity, positive predictive value, and negative predictive value of MDCT in mediastinal mass lesions assuming histopathology as gold standard.Material and methodsThis study was an analysis of 60 patients who underwent MDCT scan for characterisation of mediastinal mass lesion, and subsequently imaging findings were verified with pathological diagnosis.ResultsOut of 60 patients 65% were malignant and 35% were benign. Metastatic carcinoma was the leading diagnosis. Sensitivity of MDCT in this study came out to be 94%, specificity is 90%, with a positive predictive value of 94% and negative predictive value of 90% with diagnostic accuracy of 93%.ConclusionsMediastinal mass lesion can be accurately diagnosed with MDCT which is a non-invasive and easily available modality requiring clinical data for accurate diagnosis and management. Co-relation of MDCT findings with other imaging findings is complex and requires adequate clinical data for optimum diagnostic confidence.

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Section: Discussionsupporting

confidence: 91%

Diagnostic accuracy of multidetector computed tomography scan in mediastinal masses assuming histopathological findings as gold standard

Pandey¹,

Jaipal²,

Mannan³

et al. 2018

Pol J Radiol

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“…Iraq among 85 patients and found a similar distribution pattern of mediastinal masses (7). Moreover, two Indian studies concluded that the commonest site of the primary mediastinal tumours were in the anterior mediastinum (6,8).…”

Section: Baram Et Al Conducted a Descriptive Cross-sectional Study Inmentioning

confidence: 70%

Pathological analysis of mediastinal masses in National Hospital for respiratory diseases, Sri Lanka

et al. 2019

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IntroductionThis study describes pathological findings of mediastinal masses among patients referred to National Hospital for Respiratory Diseases. MethodsA descriptive cross-sectional study was conducted among patients with mediastinal masses referred to National Hospital for Respiratory Diseases, Welisara, Sri Lanka in 2017, who underwent excision or guided biopsy followed by standard histological and immunohistochemical staining. ResultsThe population was aged 8-75[mean (SD) =42.8(17.0)] years. Of 139 patients, 80(57.6%) were males. Masses were located in anterior mediastinum in 49.6 %( n=69), superior mediastinum in 20.1 %( n=28), middle mediastinum in 15.1 %( n=21) and posterior mediastinum in 14.4 %( n=20). Majority (65.5%, n=91) were excision biopsies. The rest were core biopsies. Commonest mass was lymphoma [n=27,19.4%;Non-Hodgkin(n=20),Hodgkin(n=7)] followed b y t h y m i c t u m o u r s [ n = 2 2 , 1 5 . 8 % ; b e n i g n ( n = 1 6 ) , malignant(n=6)], germ cell tumours (11.5%,n=16), metastatic deposits (10.8%,n=15), developmental cysts (8.6%,n=12), non-neoplastic lymphadenitis (7.9%,n=11), neuroectodermal tumours (5.8%,n=8), soft tissue sarcomas (2.9%,n=4), leiomyoma (0.7%,n=1), benign spindle cell tumour (0.7%,n=1) and plasmacytoma (0.7%,n=1). Twentyone (15.1%) specimens were either normal or inconclusive. A one-way ANOVA showed significant differences in the distribution of age among different types of masses [Welch's F (df=7, n=115) =10.09, p=.000]. Post-hoc comparisons, showed that the age of patients with germ cell tumours ( m e a n = 2 9 . 7 ± 1 1 . 5 y e a r s ) , d e v e l o p m e n t a l c y s t s (mean=38.8±16.5years) and lymphomas (mean=34.0±15.7 years) were less compared to the patients with other masses. A Chi-square test indicated no significant association between gender and the type of mediastinal mass [χ2 (df=7, n=115) =6.561, p=.48]. ConclusionsLymphoma was the commonest mediastinal mass in this population. Germ cell tumours, developmental cysts and lymphomas were commonly found among the young.

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“…The mean age of the patients in the present study was 37 years which is in concordance with other studies. [6][7][8][9][10] In the present study, precise location of the mass in the mediastinum by chest radiograph could be possible only in 32 (35.9%) patients. Although chest radiographs can show abnormalities in many patients with mediastinal masses; however, it has limited ability to delineate the extent of abnormality and relationship of masses to specific mediastinal structures.…”

Section: Figures In Parentheses Indicate Percentages Discussionmentioning

confidence: 83%

“…11 In our study, 70% of the patients were diagnosed by percutaneous FNAC/ biopsy and only 26.9% of the cases required more invasive surgical procedures, present series is similar to that from other large series across the globe. [6][7][8][9][10] The anatomical locations of various mediastinal lesions in the present study included 50.6% in the anterior; 16.9% in the middle; 10.1% in the posterior and in 22.5% in the multi-compartments. The reported anatomical locations of mediastinal lesions range for anterior mediastinal lesions was 49% to 59%; for middle mediastinal lesions, 18% to 25%; and for posterior mediastinal lesions, 23% to 27%.…”

Section: Figures In Parentheses Indicate Percentages Discussionmentioning

confidence: 99%

“…The results of comparison of present study with other studies are presented in table 7. 6,[8][9][10][18][19][20][21] like thoracotomy or mediastinoscopy. Similar observations have been made by Dubashi et al 8 Nearly 80% of patients in our study were symptomatic at the time of presentation compared to 50% to 60% in various Western studies.…”

Section: Figures In Parentheses Indicate Percentagesmentioning

confidence: 99%

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Primary Mediastinal Cysts and Tumours: A 5-Year Single Centre Experience

Singh¹,

Ahluwalia²,

Singh³

et al. 2022

The Indian Journal of Chest Diseases and Allied Sciences

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Background. Primary mediastinal lesions pose a diagnostic and management challenge and the distribution of these lesions vary depending upon the population being studied and the type of the health-care facility. Methods.A prospective, observational study of consecutive patients presenting for the evaluation of widened mediastinum on the chest radiograph was conducted during the period of January 2012 to January 2016. Patients with primary oesophageal, cardiac, pulmonary masses extending into the mediastinum, metastatic disease, infection (tuberculosis, fungal infections) and sarcoidosis were excluded.results. We studied 89 histopathological proven cases with primary mediastinal lesions; their mean age was 37.5±20.3 years; there were 50 (56.2%) males. There were 52 (58.4%) benign and 37 (41.6%) malignant lesions. In adults, 39/70 (55.7%) of masses were in the anterior, 11.4% (8/70) in the middle, 10% (7/70) in the posterior and 22.9% ( 16/70) were in multiple compartments of the mediastinum. In children, 36.8% (7/19) of the masses were in the middle, 31.6% (6/19) in anterior, 21.1% (4/19) in multiple compartment and 10.5% (2/19) in the posterior mediastinum. Lymphomas were the most common lesion 34.8% followed by thymic lesions 26.9%. conclusion. Most of the primary mediastinal lesions could be diagnosed by image guided fiberoptic needle aspiration cytology/ core biopsy. [indian j chest dis allied sci 2019;61:75-81]

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Mediastinal Masses: Retrospective Single Center Based Study

Cited by 7 publications

References 0 publications

Diagnostic accuracy of multidetector computed tomography scan in mediastinal masses assuming histopathological findings as gold standard

Diagnostic accuracy of multidetector computed tomography scan in mediastinal masses assuming histopathological findings as gold standard

Pathological analysis of mediastinal masses in National Hospital for respiratory diseases, Sri Lanka

Primary Mediastinal Cysts and Tumours: A 5-Year Single Centre Experience

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