Mediastinal thymoma invading the superior vena cava and the right atrium

Aladdin, Mohammed; Bozlar, Uğur; Turba, Ulku C.; Krön, Irving L.; Ahmed, Hossam; Hagspiel, Klaus D.

doi:10.2143/ac.62.5.2023417

Cited by 3 publications

(1 citation statement)

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“…In various studies, surgical therapy is recommended even for the SVC and RA invasion as well. 55,56 The aim of such surgeries is to achieve the blood flow from BVC to RA and complete resection which can be done by extra-anatomical grafts or cleaning of RA and SVC from tumor bulk. For grafting, we can use expanded polytetrafluoroethylene (PTFE), autologous vein, autologous or bovine pericardium while the complication of kinking and flexion is there with long conduits.…”

Section: Discussionmentioning

confidence: 99%

Feasibility of surgical procedures of invasive thymoma invading the neighbouring organs

Kumar

Jiang

2019

Int Surg J

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Thymomas are the commonest anterior mediastinal compartment neoplasm, which constitutes about 20 and 50% respectively of all mediastinal and anterior compartment tumors occurring in the adult population. The various staging systems of thymomas have been defined on the basis of the degree of invasiveness. According to the WHO classification, there are six histological types of thymic epithelial tumors. The most important prognostic factor is the stage according to Masaoka’s system. The treatment of thymomas involves combinations of surgery, radiation, and chemotherapy. The determination of which combination is chosen is reflected mostly by the stage of the disease. In the case of invasive disease, radiation therapy is often used as adjuvant treatment. Although invasive thymoma commonly infiltrates neighbouring mediastinal structures, its extension into the superior vena cava (SVC) and consequent SVC occlusion are rare. In this kind of cases, the urgent removal of the thymoma and radical resection of the tumour infiltrating the SVC represents the reasonable option.

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Section: Discussionmentioning

confidence: 99%

Feasibility of surgical procedures of invasive thymoma invading the neighbouring organs

Kumar

Jiang

2019

Int Surg J

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Thymoa presenting as an intraluminal growth into the superior vena cava and the cardiac cavity

Motoori

Shimura

Funabashi

et al. 2008

European Journal of Radiology Extra

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Thymomas With Intravascular and Intracardiac Growth

Arrossi

Dermawan²,

Bolen³

et al. 2022

Front. Oncol.

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Thymomas are derived from the epithelial component of the thymus and constitute the most common tumor of the anterior mediastinum. These neoplasms are considered malignant for their potential for invasion and metastases. Several histopathologic subclassification schemes have been proposed over the years, however, correlation of histotypes with prognosis remains controversial. In contrast, studies invariably have shown that staging and resection status correlate with oncologic behavior and disease outcomes. In this regard, several staging systems have been presented, though transcapsular invasion and degree of involvement of adjacent anatomic structures are common denominators of all schemes. Involvement of the great vessels and heart most commonly results from direct invasion, which may lead to unusual clinical presentations such as superior vena cava syndrome. Moreover, intravascular and intracardiac growth with or without direct mural invasion rarely occurs. We provide an overview of thymomas with intravascular and intracardiac involvement.

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Mediastinal thymoma invading the superior vena cava and the right atrium

Cited by 3 publications

References 0 publications

Feasibility of surgical procedures of invasive thymoma invading the neighbouring organs

Feasibility of surgical procedures of invasive thymoma invading the neighbouring organs

Thymoa presenting as an intraluminal growth into the superior vena cava and the cardiac cavity

Thymomas With Intravascular and Intracardiac Growth

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