Mediated amperometric biosensors for d-galactose, glycolate and l-amino acids based on a ferrocene-modified carbon paste electrode

Dicks, Jonathan M.; Aston, William; Davis, Graham; Turner, Anthony P. F.

doi:10.1016/s0003-2670(00)82441-1

Cited by 105 publications

(37 citation statements)

References 33 publications

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“…[95] The enzyme can be reoxidised aerobically by dioxygen or electrochemically, using mediators like ferrocene. [98] Besides its natural substrate, this oxidase accepts a wide range of primary alcohols substrates, such as glycerol, [99] 2-propyn-1-ol, and dihydroxyacetone. As an example, d/l-threitol was oxidised to yield d-threose via a kinetic resolution.…”

Section: Primary Alcohol Oxidasesmentioning

confidence: 99%

Biocatalytic Oxidation of Primary and Secondary Alcohols

et al. 2004

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Driven by the immaturity of many organic oxidation reactions and the necessity for −green× chemical processes, biocatalytic redox processes are being investigated with increasing intensity in order to tap the full potential of the excellent chemo-, regioand enantioselectivity of enzymes. Despite their unmatched advantage in view of environmental aspects, the requirement of cofactors and the availability of redox enzymes able to tolerate high concentrations of organic (co)substrates sets limitations. However, during the past years, an increasing number of applications to the bio-oxidation of primary and secondary alcohols with novel redox enzymes have been developed. This review gives an overview on the different methods and their potential and limits.

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Section: Primary Alcohol Oxidasesmentioning

confidence: 99%

Biocatalytic Oxidation of Primary and Secondary Alcohols

et al. 2004

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“…This enzyme has only been reported in one instance as being used in conjunction with carbon paste electrodes [45]. The enzyme was adsorbed on the surface of a carbon paste modified with 1,l'-dimethylferrocene.…”

Section: Sensors For Saccharidesmentioning

confidence: 99%

“…LAAOD is active with some artificial mediators, whereas DAAOD seems to be much more fastidious in its choice of electron acceptor [7]. LAAOD was one of the very first enzymes to be immobilized on the surface of a mediator modified carbon paste and used for detection of L-leucine [45]. Both enzymes have been successfully co-immobilized with different peroxidases (HRP and ARP) in carbon pastes [76,129,147,148,1501.…”

Section: Sensors For Amino Acidsmentioning

confidence: 99%

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Carbon paste electrodes modified with enzymes, tissues, and cells

1995

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A review is presented dealing with the use of carbon paste amperometric electrodes for electroanalytical purposes, with either the surface or the bulk being modified with biologically derived material such as enzymes, tissues, and cells. It covers virtually all the publications which have appeared from the very first enzyme-modified carbon paste electrode up to early 1994 and includes 220 references.

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“…In particular, glucose oxidase has been investigated closely because it catalyzes an easily handled enzymatic reaction and produces hydrogen peroxide, which shows good voltammetric properties [ 143-1451, Dicks et al achieved voltammetric sensing by using carbon paste electrodes that had been modified with ferrocene by direct mixing, further modified with adsorption of an oxidase, and additionally protected with a membrane [134]. An improvement was made by adding the enzyme directly to the paste and by attaching the ferrocene to siloxane polymers over flexible side chains, which prevents the complex from difhsing away from the electrode surface [ 1351.…”

Section: Biological Modi@rsmentioning

confidence: 99%