Marriage affects people's happiness and lifetime. Researches support the idea that married people are healthier and happier and they have longevity than other people (single, divorced and widowed). In the world, incidence of neurological diseases increases day by day and they may affect patients, their families and societies. However, marital status, marital relationship, and spouse's situation affect illness acceptance and cope with illness. In the literature, it is stated that married patients are healthier and have long life span than other patients with neurological diseases such as Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis (MS), Alzheimer Disease (AD), Parkinson's Disease (PD) and stroke. On the other hand, diseases such as MS and epilepsy may be risk factor to divorce or negatively affect their spouses or marital relationship in married patients. In our study, we aimed to examine the relation between neurological diseases and marital status, divorce, spouses' situation and marital relationship.