Medical Abortion: Use of Mifepristone and Misoprostol in First and Second Trimesters of Pregnancy

Patil, Eva; Edelman, Alison

doi:10.1007/s13669-014-0109-4

Cited by 7 publications

(6 citation statements)

References 96 publications

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“…Residual intrauterine pregnancy tissue is a residual appendage or detrusor that remains in the uterine cavity after termination of intrauterine pregnancy, which can cause recurrent vaginal bleeding or uterine infection, and is also an important cause of abortion or postpartum uterine bleeding and infection [ 1 ]. Abdominal ultrasound can clearly observe whether there is residual pregnancy tissue in the uterus, and if there is residual tissue, the results of the examination can show the size and location of the residual tissue and its relationship with the myometrial wall of the patient, which can provide accurate and reliable diagnostic basis for medical personnel to formulate appropriate treatment measures and reduce the occurrence of bleeding and infection to a certain extent.…”

Section: Introductionmentioning

confidence: 99%

B-Ultrasound Image Analysis of Intrauterine Pregnancy Residues after Mid-Term Pregnancy Based on Smart Medical Big Data

Liu

Zhou

et al. 2022

Journal of Healthcare Engineering

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Abdominal B-ultrasound images of intrauterine pregnancy tissue residues were analyzed to discuss their diagnostic value. With the rapid development of computer technology and medical imaging technology, doctors are also faced with more and more medical image diagnosis tasks, and computer-aided diagnosis systems are especially important in order to reduce the work pressure of doctors. In recent years, deep learning has made rapid development and achieved great breakthroughs in various fields. In medical-aided diagnostic systems, deep learning has greatly improved the diagnostic efficiency, but there are no mature research results for abdominal B-ultrasound image recognition of intrauterine pregnancy tissue residues. Therefore, the study of liver ultrasound image classification based on deep learning has important practical application value. In this paper, we propose to give a CNN model optimization method based on grid search. Compared with the conventional CNN model design, this method saves time and effort by eliminating the need to manually adjust parameters based on experience and has an accuracy of more than 92% in classifying abdominal B-ultrasound images of intrauterine pregnancy tissue residues. The diagnosis of intrauterine pregnancy tissue residues by abdominal B-ultrasound can effectively improve the diagnosis and provide important reference for patients to receive treatment, which has high diagnostic value.

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Section: Introductionmentioning

confidence: 99%

B-Ultrasound Image Analysis of Intrauterine Pregnancy Residues after Mid-Term Pregnancy Based on Smart Medical Big Data

Liu

Zhou

et al. 2022

Journal of Healthcare Engineering

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“…[ 5 ] If they are not removed in time, it may influence menstrual flow and the intrauterine environment, and even induce heavy bleeding, imperiling patient’s life. [ 6 , 7 ] Thus, diagnosing whether there is intrauterine residue after medical abortion early is exceedingly pivotal. Transvaginal color Doppler ultrasonography is currently the cardinal approach for detecting and diagnosing whether there is intrauterine residue after medical abortion, which is leadingly determined by observing whether there are abnormal echoes and lesions in the uterus.…”

Section: Introductionmentioning

confidence: 99%

The diagnostic value of transvaginal color Doppler ultrasonography plus serum β-HCG dynamic monitoring in intrauterine residue after medical abortion

Liu

Lv²

2023

Medicine

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To probe the diagnostic value of transvaginal color Doppler ultrasonography plus serum β-human chorionic gonadotropin (β-HCG) dynamic monitoring in intrauterine residue after medical abortion.In total, 200 pregnant women undergoing medical abortion in our institution from January 2017 to December 2019 were picked, and assigned to either group A (n = 75, with residue) or group B (n = 125, without residue). We detected serum β-HCG, progesterone (P), follicle stimulating estrogen (FSH) levels and ultrasonic indicators endometrial thickness (ET), peak systolic velocity (PSV), resistance index (RI) values, dissected correlation of indicators using logistic linear regression analysis, and prospected the diagnostic value of relevant indicators in intrauterine residue after medical abortion utilizingreceiver operating characteristic curve.At 7 days after abortion (T3), total vaginal bleeding and visual analogue scalescore in group A were saliently higher in contrast to group B ( P < .05). At 72 hours after abortion (T2) and T3, serum β-HCG, P and FSH levels declined strikingly in both groups, but group B held plainly higher decrease rate than group A ( P HC.05). At T3, ET and PSV levels in both groups considerably waned, whereas RI levels notedly waxed, and group B owned markedly higher decrease/increase than group A ( P wa.05). At T3, serum β-HCG in group A possessed positive association with serum P, FSH, intrauterine ET, PSV levels separately ( P HC.05), whereas negative link with RI levels ( P , .05). The specificity and sensitivity of β-HCG, P, FSH, β-HCG/ET, β-HCG/PSV and β-HCG/RI in the diagnosis of intrauterine residue after medical abortion were high ( P < .05).Serum β-HCG dynamic monitoring plus transvaginal color Doppler ultrasonography is of great value in diagnosing intrauterine residue after medical abortion. Serum β-HCG, P, FSH levels can be combined with the results of intrauterine ET, PSV, RI values, so as to boost the diagnostic accuracy of the intrauterine residue after medical abortion.

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“…Nonsurgical alternatives expand a woman's treatment options and, in turn, the quality of care [4] . Misoprostol as it is cheap and stable at room temperature; it has been shown to be effective for first trimester termination of pregnancy [5] .…”

Section: Introductionmentioning

confidence: 99%

Misoprostol Versus Manual Vacuum Aspiration in Treatment of Missed Miscarriage in First Trimester

Allakany

2021

The Medical Journal of Cairo University

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Background: Manual vacuum aspiration (MVA) is a safe and effective technology for the treatment of missed miscarriage but it is not widely available and affordable in rural areas particularly in low resource countries. Misoprostol is an alternative to manual vacuum aspiration for the treatment of missed miscarriage. Aim of Study:The purpose of this study was to compare the effectiveness, patient satisfaction and hematocrit drop of misoprostol versus MVA to understand the potential role of misoprostol as a first line for treatment of first trimester missed miscarriage.Patients and Methods: A Randomized Controlled Trial was conducted from January 2020 to January 2021 at Mansoura University Maternity Hospital. Included 70 participants were randomized to treatment with either MVA or 800 µg vaginal misoprostol. The main outcome measures assessed at 1 week follow up were complete uterine evacuation, patient's acceptability and satisfaction.Results: There is no statistically significant difference between studied groups regarding success rate and mean patient satisfaction score immediately and after one week, 82.9% of misoprostol group and 94.3% of MVA group successes. The mean hemoglobin and hematocrit after treatment illustrated statistically significant lower mean value among misoprostol group than MVA group (10.07 & 10.91, respectively for Hb) and (30.75 & 33, respectively for hematocrit value). Hemoglobin drop for both groups illustrated no statistically significant difference between studied groups. There is statistically significant negative correlation between endometrial thickness/mm and satisfaction after one week among both group. Conclusion:Both misoprostol and MVA had high rates of satisfaction and complete uterine evacuation, which could ultimately reduce maternal complications from abortion. Medical treatment is as effective as surgical treatment of first trimester missed miscarriages.Recommendations: Although misoprostol is a very effective drug, the health care professional should have thorough knowledge of the dose, side effects, complications and con-

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Medical Abortion: Use of Mifepristone and Misoprostol in First and Second Trimesters of Pregnancy

Cited by 7 publications

References 96 publications

B-Ultrasound Image Analysis of Intrauterine Pregnancy Residues after Mid-Term Pregnancy Based on Smart Medical Big Data

B-Ultrasound Image Analysis of Intrauterine Pregnancy Residues after Mid-Term Pregnancy Based on Smart Medical Big Data

The diagnostic value of transvaginal color Doppler ultrasonography plus serum β-HCG dynamic monitoring in intrauterine residue after medical abortion

Misoprostol Versus Manual Vacuum Aspiration in Treatment of Missed Miscarriage in First Trimester

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