Introduction. Medical and economic analysis makes it possible to evaluate the effectiveness of medical organizations and justify management decisions to optimize their activities. The purpose of the study: to conduct a medical and economic analysis of the activities of medical organizations in St. Petersburg in providing medical care to patients with injuries in inpatient settings. Materials and methods: according to the data of the Territorial Compulsory Medical Insurance Fund, a patient register has been formed with injuries (ICD-10 codes: S00.0–T09.9) for the period 01.01.2015–31.12.2023, n=1269235. The peculiarities of the application of compulsory health insurance tariffs for adults and children have been studied: The 1st group consisted of patients discharged from the emergency department (inpatient emergency department), the 2nd group consisted of patients admitted to the hospital and not treated in the intensive care unit, the 3rd group consisted of patients treated in the intensive care unit. The results of the study. During the specified period, the number of cases of inpatient medical care for patients with injuries in St. Petersburg decreased: among adult patients — by 32.5%, among children — by 50.3%; the decrease was due to a decrease in the number of patients of the 1st group. At the same time, the proportion of 1st group patients who received medical care in emergency beds (without hospitalization in hospital departments) increased: among adult patients to 65.1%, among children — to 20.1%. The cost of compulsory medical insurance to pay for medical care for adult patients increased by 66.9% to 1999.3 thousand rubles; the cost of paying for medical care for children increased by 71.0% to 575.6 thousand rubles.