Medical application of particle and heavy ion transport code system PHITS

Furuta, Takuya; Sato, Tatsuhiko

doi:10.1007/s12194-021-00628-0

Cited by 26 publications

(7 citation statements)

References 101 publications

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“…The production of secondary neutrons in CIRT is also verified compared to experiments (Yonai et al 2010). The review of medical applications of PHITS is given in the literature (Furuta and Sato 2021).…”

Section: Simulationmentioning

confidence: 84%

Development of the DICOM-based Monte Carlo dose reconstruction system for a retrospective study on the secondary cancer risk in carbon ion radiotherapy

Furuta¹,

Koba²,

Hashimoto³

et al. 2022

Phys. Med. Biol.

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Objective. A retrospective study on secondary cancer risk on carbon ion radiotherapy (CIRT) is ongoing at the Heavy Ion Medical Accelerator in Chiba (HIMAC). The reconstruction of the whole-body patient dose distribution is the key issue in the study because dose distribution only around the planning target volume was evaluated in the treatment planning system. Approach. We therefore developed a new dose reconstruction system based on the Particle and Heavy Ion Transport code System (PHITS) coupled with the treatment plan DICOM data set by extending the functionalities of RadioTherapy package based on PHITS (RT-PHITS). In the system, the geometry of patient-specific beam devices such as the range shifter, range compensator, and collimators as well as the individual patient’s body are automatically reconstructed. Various functions useful for retrospective analysis on the CIRT are implemented in the system, such as those for separately deducing dose contributions from different secondary particles and their origins. Main results. The accuracy of the developed system was validated by comparing the dose distribution to the experimental data measured in a water tank and using a treatment plan on an anthropomorphic phantom. Significance. The extended RT-PHITS will be used in epidemiological studies based on clinical data from HIMAC.

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Section: Simulationmentioning

confidence: 84%

Development of the DICOM-based Monte Carlo dose reconstruction system for a retrospective study on the secondary cancer risk in carbon ion radiotherapy

Furuta¹,

Koba²,

Hashimoto³

et al. 2022

Phys. Med. Biol.

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“…Thus, it was speculated that the beam spreading and generating secondary particles were more complicated. Further investigations using a simulation such as the PHTIS code [ 60 , 61 , 62 ] are required.…”

Section: Resultsmentioning

confidence: 99%

Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid T1 Mapping Method

Mizukami

Watanabe

Mizoguchi

et al. 2021

Gels

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MRI-based gel dosimeters are attractive systems for the evaluation of complex dose distributions in radiotherapy. In particular, the nanocomposite Fricke gel dosimeter is one among a few dosimeters capable of accurately evaluating the dose distribution of heavy ion beams. In contrast, reduction of the scanning time is a challenging issue for the acquisition of three-dimensional volume data. In this study, we investigated a three-dimensional dose distribution measurement method for heavy ion beams using variable flip angle (VFA), which is expected to significantly reduce the MRI scanning time. Our findings clarified that the whole three-dimensional dose distribution could be evaluated within the conventional imaging time (20 min) and quality of one cross-section.

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“…Therefore, after confirming that the planned and measured doses were equivalent, the film was calibrated based on the planned dose. To examine the relationship between the deviation of the film dose and LET, the dose-averaged LET at each measurement depth was estimated by the Monte Carlo simulation PHITS (ver.3.24) [18] , [19] , [20] .…”

Section: Methodsmentioning

confidence: 99%

Linear energy transfer-independent calibration of radiochromic film for carbon-ion beams

Tashiro

Kawashima

2022

Physics and Imaging in Radiation Oncology

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Medical application of particle and heavy ion transport code system PHITS

Cited by 26 publications

References 101 publications

Development of the DICOM-based Monte Carlo dose reconstruction system for a retrospective study on the secondary cancer risk in carbon ion radiotherapy

Development of the DICOM-based Monte Carlo dose reconstruction system for a retrospective study on the secondary cancer risk in carbon ion radiotherapy

Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid T1 Mapping Method

Linear energy transfer-independent calibration of radiochromic film for carbon-ion beams

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