Medical Applications of Accelerators

Eickhoff, H.; Linz, Ute

doi:10.1142/s1793626808000083

Cited by 9 publications

(5 citation statements)

References 47 publications

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“…Nowadays different types of hadron and electron accelerators are used for medical application [228]. According to Ref.…”

Section: Hadron Therapy Acceleratormentioning

confidence: 99%

Beam Diagnostic Requirements: an Overview

Kube

2020

Preprint

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Beam diagnostics and instrumentation are an essential part of any kind of accelerator. There is a large variety of parameters to be measured for observation of particle beams with the precision required to tune, operate, and improve the machine. In the first part, the basic mechanisms of information transfer from the beam particles to the detector are described in order to derive suitable performance characteristics for the beam properties. However, depending on the type of accelerator, for the same parameter, the working principle of a monitor may strongly differ, and related to it also the requirements for accuracy. Therefore, in the second part, selected types of accelerators are described in order to illustrate specific diagnostics needs which must be taken into account before designing a related instrument.

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“…Nowadays different types of hadron and electron accelerators are used for medical application [228]. According to Ref.…”

Section: Hadron Therapy Acceleratormentioning

confidence: 99%

Beam Diagnostic Requirements: an Overview

Kube

2020

Preprint

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“…The prominence of the Bragg peak is higher for heavier ions compared to protons. In addition, heavier ions deposit a significantly higher amount of energy in the cells, and have stronger relative biological effect (RBE) [1] owing to a higher frequency of double-strand DNA breakups. Ion RBE is especially enhanced in the area of the Bragg peak.…”

Section: Motivationmentioning

confidence: 99%

“…This makes IBT the method of choice for treating patients with radiation-resistant tumors. It is estimated that for a population of 10 million the annual number of patients requiring IBT amounts to 4500 [1]. Contemporary IBT facilities, such as HIMAC in Japan [2] and HIT in Germany [3], are designed to treat 800 and 750 patients a year, respectively.…”

Section: Motivationmentioning

confidence: 99%

Advanced Electron Beam Ion Sources (EBIS) for 2-nd generation carbon radiotherapy facilities

Shornikov¹,

Wenander²

2016

J. Inst.

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In this work we analyze how advanced Electron Beam Ion Sources (EBIS) can facilitate the progress of carbon therapy facilities. We will demonstrate that advanced ion sources enable operation of 2-nd generation ion beam therapy (IBT) accelerators. These new accelerator concepts with designs dedicated to IBT provide beams better suited for therapy and, are more cost efficient than contemporary IBT facilities. We will give a sort overview of the existing new IBT concepts and focus on those where ion source technology is the limiting factor. We will analyse whether this limitation can be overcome in the near future thanks to ongoing EBIS development. K: Instrumentation for heavy-ion therapy; Instrumentation for hadron therapy; Instrumentation for particle-beam therapy 1Corresponding author.

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“…But with the advent of new generations of low cost turnkey accelerators, dedicated to industrial use, treatment center projects are multiplying (CNAO, HIT, MEDAUSTRON, ARCHADE, only to mention Europe) [5]. Pending the construction of these new centers, the demands of beam time for research purposes are increasingly important, which mainly explains the use of structures originally designed for other applications.…”

Section: Introductionmentioning

confidence: 99%

Dosimetry for radiobiology experiments at GANIL

Durantel

Balanzat

Cassimi

et al. 2016

Nuclear Instruments and Methods in Physics Research Section A:

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International audienceMainly encouraged by the increasing application of ion beams for cancer treatment (hadron-therapy) including carbon beams, the use of heavy ion facilities for radiobiology is expanding rapidly today. As an alternative to dedicated centers for treatment and medical research, accelerators like GANIL offer the possibility to undertake such experiments.Since 20 years, CIMAP, reinforced 15 years ago by the biological host laboratory LARIA, has been receiving researchers in radiobiology and assisted them in performing experiments in different fields such as hadron-therapy, space radioprotection and fundamental biological and physico-chemical mechanisms. We present here a short description of the beam line and the on-line equipments that allow the automatic irradiation of up to 24 biological samples at once.We also developed an original on-line beam monitoring procedure for low ion flux (low dose rates) based on the measurement of the K-shell X-rays emitted from a thin iron foil. This detector is calibrated on an absolute scale before each experiment by counting etched tracks on an irradiated CR39 polymer plate. We present the performances and limits of this method and finally give typical fluence (dose) uncertainties for a standard irradiation in radiobiology

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Medical Applications of Accelerators

Cited by 9 publications

References 47 publications

Beam Diagnostic Requirements: an Overview

Beam Diagnostic Requirements: an Overview

Advanced Electron Beam Ion Sources (EBIS) for 2-nd generation carbon radiotherapy facilities

Dosimetry for radiobiology experiments at GANIL

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