Medical countermeasure against respiratory toxicity and acute lung injury following inhalation exposure to chemical warfare nerve agent VX

Protective Effect of Reversible Cholinesterase Inhibitors (Tacrine, Pyridostigmine) and EqBuChE against VX Poisoning and Brain Acetylcholinesterase Inhibition in Rats

“…AChE activity in the pontomedullar part of the brain is sensitive to nerve agents including VX as demonstrated previously (7). It is known that sublethal concentrations of VX, induce changes in respiratory dynamics and ventilation in guinea pigs (39) treatable with pulmonary therapeuticals (30).…”

Assessment of Potential Long Term Health Effects on Army Human Test Subjects of Relevant Biological and Chemical Agents, Drugs, Medications and Substances

“…227 In 2013, Talukdar also reported a case of mixed catatonia and Parkinsonism as sequelae to typhoid fever in an 18-year old man. 232 This case, although severe, and included periods of total paralysis, resolved with appropriate treatment four weeks after hospital discharge. The mechanism by which typhoid fever may produce neurological illness is still unknown, but it is possible that S. enterica, var.…”

Organophosphate Insecticide Intoxication in a Family

“…The most common cause of death in this kind of poisoning are respiratory failure due to respiratory centers depression, respiratory muscle weakness, suppression of the central nervous system, and bronchorrhea [10]. Diagnosis of OP is based on patient's history, clinical status, and laboratory tests.…”