Medical ethnobotany of the Siddis of Uttara Kannada district, Karnataka, India

Bhandary, M Jayakara; Chandrashekar, K. R.; Kaveriappa, K. M.

doi:10.1016/0378-8741(95)01274-h

Cited by 251 publications

(120 citation statements)

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“…The plant is used in traditional system of medicine. The rhizome is used in the treatment of diabetes (Bhandary et al 1995), fever (as febrifuge) and headache (Jain et al 1995), arthritis, inflammation and skin diseases (Kiem et al 2012). The paste prepared from the rhizome is applied externally in cases of snakebite (Ray et al 2011).…”

Section: Introductionmentioning

confidence: 99%

Micropropagation of Hedychium coronarium J. Koenig through rhizome bud

Mohanty

Behera

Swain

et al. 2013

Physiol Mol Biol Plants

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An optimized protocol was developed for in vitro plant regeneration of a medicinally important herb Hedychium coronarium J. Koenig using sprouted buds of rhizomes. The rhizomes with sprouted bud were inoculated on Murashige and Skoog (Physiol Plant 15:473-497, 1962) was most effective. In this medium, best shoots (3.6) and roots (4.0) regeneration was observed simultaneously with an average shoot and root length of 4.7 cm and 4.2 cm respectively. Regeneration of shoots and roots in the same medium at the same time (One step shoot and root regeneration) reduced the time for production of in vitro plantlets and eliminates the media cost of rooting. Cent-percent (100 %) success in plant establishment was observed in both gradual acclimatization process as well as when plants were directly transferred to outdoor in clay pots containing a mixture of garden soil and sand (2:1) without any sequential acclimatization stage.

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Section: Introductionmentioning

confidence: 99%

Micropropagation of Hedychium coronarium J. Koenig through rhizome bud

Mohanty

Behera

Swain

et al. 2013

Physiol Mol Biol Plants

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“…Stem barks of Careya arborea was traditionally used in the treatment of tumors, anthelmintic, bronchitis, epileptic fits, astringents, antidote to snake-venom and skin disease (Kirtikar and Basu, 1975). It also used as remedy for diarrhea (Sikarwar et al, 1994), dysentery with bloody stools and ear pain (Girach et al, 1994;Bhandary et al, 1995). Antipyretic (Das and Mahato, 1982), leech repellent, fish poison and antivenin activities were also reported in literature (Talapatra et al, 1981;John, 1984;Selvanayahgam et al, 1994).…”

Section: Introductionmentioning

confidence: 99%

Antitumor effect of Careya arborea against Ehrlich ascites carcinoma with reference to lipid peroxidation and enzymatic and non enzymatic antioxidant system in Swiss albino mice

Sambathkumar¹,

Sivakumar²,

Senthil³

et al. 2008

Oriental Pharmacy and Experimental Medicine

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SUMMARYThe methanol extract of stem barks of Careya arborea Roxb. (MECA) (Family-Myrtaceae) was evaluated for antitumor activity and antioxidant status against Ehrlich's Ascites Carcinoma (EAC) bearing Swiss albino mice. After 24 h of tumor inoculation the MECA was administered at the doses of 50, 100 and 200 mg/kg body weight/mice/day for 14 days. After the last dose and 18 h fasting mice were sacrificed. The effect of MECA on the growth of transplantable murine tumor, life span of EAC bearing hosts, hematological profiles, serum and liver biochemical parameters were estimated. The MECA showed significant (P < 0.01) decrease in ascites volume, packed cell volume and viable cell count and prolonged the life span of EAC tumor bearing mice. Hematological profiles reverted to more or less normal levels in extract treated mice. The MECA also produced protective effect by decreasing the activity of serum enzymes, bilirubin and increase the protein and uric acid levels. MECA significantly (P < 0.05) decreased the levels of lipid peroxidation, while significantly (P < 0.05) increased the levels of glutathione content, vitamin C, vitamin E, superoxide dismutase and catalase CAT. The results indicate that MECA exhibited significant antitumor and antioxidant activity in EAC bearing mice.

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“…Apart from that, the stem is also widely used to treat asthma. It has been also reported that the whole plant is used against various health problems and disorders such as diarrhea 13 , small pox 14 , muscle catches, sprains 15 and bone fracture. 16 Recently, the ethanolic extract of P. scandens has been reported to be effective in wound healing 17 and the plant has also been reported to have significant antioxidant and antipyretic activity.…”

Section: Introductionmentioning

confidence: 99%

Therapeutic Effect of Hydro-Ethanolic Extract of Pothos scandens L on key Carbohydrate Metabolizing Enzymes and Xenobiotic Marker Enzymes in DMBA Induced Experimental Mammary Carcinoma

Prasannakumari¹,

Padmam²,

Doss³

2017

IJPER

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Objective: In the present study, phytochemical evaluation and the therapeutic effect of 50 % hydro-ethanolic extract of aerial parts of Pothos scandens (HEEPS) on glycolytic enzymes, TCA cycle enzymes, gluconeogenic enzymes and xenobiotic marker enzymes in the liver and breast tissues of 7, 12 -Dimethylbenz [a] anthracene (DMBA) induced breast cancer bearing rats were carried out. Materials and Methods: Five groups of (each group six rats) female albino Spargue-Dawley rats were taken. Group I (control), Group II (DMBA induced, 20 mg/ kg b.wt p.o), Group III (DMBA + Cyclophoshamide, 10mg/kg b.wt p.o), Group IV (DMBA + 200 mg/kg b.wt p.o of HEEPS) and Group V (DMBA + 400 mg/kg b.wt p.o of HEEPS). The alteration in the level of carbohydrate metabolizing enzymes such as Hexokinase, Phosphogluco isomerase, Glucose-6-phosphatase, Fructose-1,6-bis phosphatase, Succinate dehydrogenase and Malate dehydrogenase together with the level of xenobiotic markers like Cytochrome P450 reductase, Cytochrome C oxidase and Glutathione -S-transferase were analyzed in all the groups. GC-MS analysis of the plant extract was also carried out. Results: Increased level of glycolytic enzymes, decreased level of TCA cycle enzymes, gluconeogenic enzymes and altered level of xenobiotic marker enzymes observed in Group II was brought to near normal in treatment groups in a dose dependent manner suggesting potential anticancer activity of HEEPS. This was supported by the GC-MS analysis of the plant extract which revealed the presence of many compounds with anticancer activity. Conclusion: The study revealed that HEEPS is effective in restoring the activity of mitochondria in DMBA induced breast cancer.

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Medical ethnobotany of the Siddis of Uttara Kannada district, Karnataka, India

Cited by 251 publications

References 1 publication

Micropropagation of Hedychium coronarium J. Koenig through rhizome bud

Micropropagation of Hedychium coronarium J. Koenig through rhizome bud

Antitumor effect of Careya arborea against Ehrlich ascites carcinoma with reference to lipid peroxidation and enzymatic and non enzymatic antioxidant system in Swiss albino mice

Therapeutic Effect of Hydro-Ethanolic Extract of Pothos scandens L on key Carbohydrate Metabolizing Enzymes and Xenobiotic Marker Enzymes in DMBA Induced Experimental Mammary Carcinoma

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