MICHELANGELO addresses a specific category of patients i.e. the autistic children; the aim is to use ICT to promote and facilitate the assessment of autism within the home setting, away from the traditional clinical environments and to provide personalized "home-based" intervention strategies. This is achieved through the provision of cost-effective, patient-centric home-based intervention remotely controlled by the therapist (remote rehabilitation). The proposed method aims at enhancing the effectiveness of the treatment through its "intensiveness" and "personalization" matching the individual characteristics of autistic children and the involvement of the parents in their "natural" home environment in the role of "co-therapists". Both projects offer interesting inputs on how Information and Communication