Medical (fluoxetine) and psychological (cognitive–behavioural therapy) treatment for premenstrual dysphoric disorder

Hunter, Myra; Ussher, Jane M.; Cariss, Margaret; Browne, Susannah; Jelley, R. Blake; Katz, Maurice

doi:10.1016/s0022-3999(02)00338-0

Cited by 58 publications

(44 citation statements)

References 16 publications

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“…For example, several trials demonstrated the efficacy of behavioural activation to reduce depressive symptoms [55]. Our findings are also in line with the results of a study comparing CBT and medical treatment for PMDD [23]: after treatment, there was a significant increase in the use of active behavioural coping strategies in the CBT group only. In addition, active behavioural coping was related to better outcome at the 1-year FU [23].…”

Section: Discussionsupporting

confidence: 90%

“…One of the higher-quality studies was conducted by Hunter et al [9] and compared CBT with pharmacological treatment (i.e., fluoxetine). Both treatments were effective, with fluoxetine showing a more rapid effect and greater impact on anxiety symptoms, and CBT showing an increase in cognitive and behavioural coping strategies [23]. Importantly, active behavioural coping was associated with a good outcome at the 1-year follow-up.…”

Section: Introductionmentioning

confidence: 99%

“…Importantly, active behavioural coping was associated with a good outcome at the 1-year follow-up. In the CBT group, the number of cases with PMDD at the follow-up was smaller than in the fluoxetine group [23]. These results show the potential of CBT as a promising treatment option resulting in long-term stable improvements and indicate the important role of coping strategies [24].…”

Section: Introductionmentioning

confidence: 99%

“…Women with premenstrual syndrome (PMS) show continuous abnormalities in stress reactivity independent of their menstrual cycle phase [31]. Active behavioural coping strategies have been demonstrated to be a significant predictor of a positive outcome in a CBT for women with PMS in a previous trial [23]. We hypothesized that active coping strategies and a lower level of perceived stress are associated with a better outcome in this Internet-based treatment.…”

Section: Introductionmentioning

confidence: 99%

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Internet-Based Cognitive-Behavioural Intervention for Women with Premenstrual Dysphoric Disorder: A Randomized Controlled Trial

Weise

Kaiser

Janda

et al. 2019

Psychother Psychosom

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Background: Given the high prevalence of clinically relevant premenstrual symptoms and the associated impairment, there is a need for effective treatments. Initial evidence suggests cognitive-behavioural therapy (CBT) as an effective treatment for premenstrual dysphoric disorder (PMDD). The aim of the current randomized clinical trial was to evaluate an Internet-based CBT (iCBT) to reduce the burden of PMDD. Methods: In all, 174 women with PMDD were recruited via newspaper articles, flyers, and social media. They were randomized to a treatment group (TG; n = 86) or waitlist control group (CG; n = 88). Women of the TG received an 8-week therapist-guided iCBT. Data were assessed before and after treatment/waiting, and 6 months after intervention with prospective symptom diaries and questionnaires in the premenstrual phase. Treatment effects and moderators were analysed using hierarchical linear modelling. Results: Significant time × group interaction effects on functional impairment and psychological impairment, impact on everyday life, symptom intensity, and symptom disability in favour of the TG indicated the efficacy of the treatment. Follow-up assessments demonstrated treatment effects to be stable until 6 months after treatment. Additionally, significant interactions with moderator variables were found. In the TG, higher levels of active coping and lower levels of support-seeking coping were associated with stronger improvement in interference in everyday life and symptom intensity. In addition, lower levels of perceived stress were associated with stronger improvement in functional impairment. Conclusion: The iCBT was highly effective in reducing the burden of PMDD. It appears to be particularly important to address coping styles and stress management in the treatment.

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Section: Discussionsupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Internet-Based Cognitive-Behavioural Intervention for Women with Premenstrual Dysphoric Disorder: A Randomized Controlled Trial

Weise

Kaiser

Janda

et al. 2019

Psychother Psychosom

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“…152 Another RCT examined the relative efficacy of fluoxetine 20 mg daily, 10 individual CT sessions or their combination in women with PMDD. 153,154 Efficacy rates at 6 months were comparable between the 3 treatments; however, at 1 year women who had received CT were coping better than those who had received fluoxetine alone. Relaxation has had little systematic study in PMS; a single RCT reported that relaxation therapy was superior to both symptom charting and leisure reading.…”

Section: Lifestyle Modifications and Psychosocial Treatmentsmentioning

confidence: 91%

Premenstrual Dysphoric Disorder: Burden of Illness and Treatment Update

Pearlstein¹,

Steiner²

2012

FOC

103

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291Five percent of menstruating women have severe premenstrual symptoms and impairment of functioning defined as premenstrual dysphoric disorder (PMDD). Clinically significant premenstrual symptoms occur in at least an additional 20% of menstruating women. The diagnosis of PMDD should be confirmed by prospective symptom charting over 2 menstrual cycles to confirm the timing of the symptoms and to rule out other diagnoses. The burden of illness of PMDD includes disruption of parenting and partner relationships and decreased productivity in work roles. In addition, women with PMDD have increased use of health care services such as clinician visits and increased use of prescription medications and over-the-counter preparations. The etiology of PMDD is multifactorial. In particular, dysregulation of the serotonin and allopregnanolone systems is implicated. Several effective treatment options exist, including serotonergic antidepressant medications and an oral contraceptive that contains ethinyl estradiol and drosperinone. In addition, other hormones that suppress ovulation, anxiolytics, cognitive therapy, chasteberry and calcium may be helpful.Cinq pour cent des femmes menstruées ont des symptômes prémenstruels sévères et une incapacité du fonctionnement appelée trouble dysphorique prémenstruel (TDPM). Au moins 20 % de femmes menstruées de plus ont des symptômes prémenstruels cliniquement significatifs. Il faut confirmer le diagnostic de TDPM en suivant les symptômes de façon prospective au cours de deux cycles menstruels afin de confirmer le moment de l'apparition des symptômes et d'exclure d'autres diagnostics. Le fardeau morbide imposé par le TDPM comprend la perturbation des relations avec les enfants et le partenaire et une baisse de productivité au travail. Les femmes atteintes de TDPM ont en outre recours davantage aux services de santé comme les visites aux cliniciens et prennent davantage de médicaments d'ordonnance et en vente libre. L'étiologie du TDPM est multifactorielle. La dysrégulation des systèmes de la sérotonine et de l'allopregnanolone en particulier est mise en cause. Il existe plus d'un traitement efficace possible, y compris des antidépresseurs sérotonin-ergiques et un contraceptif oral qui contient de l'éthinyloestradiol et de la drosperinone. D'autres hormones qui bloquent l'ovulation, des anxiolytiques, la thérapie cognitive, le gattilier (Vitex agnus castus) et le calcium peuvent en outre aider. Review Paper Examen critique DiagnosisAbout 80% of women report at least mild premenstrual symptoms, 20%-50% report moderate-to-severe premenstrual symptoms, and about 5% report severe symptoms for several days with impairment of functioning.

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Depressive Disorders: Premenstrual Dysphoric Disorder

Pearlstein

2015

Psychiatry

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Medical (fluoxetine) and psychological (cognitive–behavioural therapy) treatment for premenstrual dysphoric disorder

Cited by 58 publications

References 16 publications

Internet-Based Cognitive-Behavioural Intervention for Women with Premenstrual Dysphoric Disorder: A Randomized Controlled Trial

Internet-Based Cognitive-Behavioural Intervention for Women with Premenstrual Dysphoric Disorder: A Randomized Controlled Trial

Premenstrual Dysphoric Disorder: Burden of Illness and Treatment Update

Depressive Disorders: Premenstrual Dysphoric Disorder

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