Medical imaging in pediatric ophthalmology

Mafee, Mahmood F.; Mafee, Rana F.; Malik, Mahr; Pierce, J.A.

doi:10.1016/s0031-3955(03)00002-6

Cited by 23 publications

(24 citation statements)

References 37 publications

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“…CT was the first imaging modality used to detect optic nerve invasion [51–53] and is historically assumed to be precise in detection of tumor extent [54–56]. However, this assumption is based on conflicting outdated literature, without thorough evidence by radiologic-pathologic correlation studies.…”

Section: Choice Of Imaging Modalitymentioning

confidence: 99%

Guidelines for imaging retinoblastoma: imaging principles and MRI standardization

Göricke²,

et al. 2011

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Retinoblastoma is the most common intraocular tumor in children. The diagnosis is usually established by the ophthalmologist on the basis of fundoscopy and US. Together with US, high-resolution MRI has emerged as an important imaging modality for pretreatment assessment, i.e. for diagnostic confirmation, detection of local tumor extent, detection of associated developmental malformation of the brain and detection of associated intracranial primitive neuroectodermal tumor (trilateral retinoblastoma). Minimum requirements for pretreatment diagnostic evaluation of retinoblastoma or mimicking lesions are presented, based on consensus among members of the European Retinoblastoma Imaging Collaboration (ERIC). The most appropriate techniques for imaging in a child with leukocoria are reviewed. CT is no longer recommended. Implementation of a standardized MRI protocol for retinoblastoma in clinical practice may benefit children worldwide, especially those with hereditary retinoblastoma, since a decreased use of CT reduces the exposure to ionizing radiation.

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Section: Choice Of Imaging Modalitymentioning

confidence: 99%

Guidelines for imaging retinoblastoma: imaging principles and MRI standardization

Göricke²,

et al. 2011

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“…MR imaging is the method of choice in depicting ocular lesions; 8,11,[25][26][27] however, CT is still the method of choice for detecting intraocular calcium and investigating orbital pathologies. 28,29 The disadvantages of CT are reduced soft-tissue contrast and spatial resolution compared with MR imaging; the presence of the potential risk of iodinated contrast administration; and radiation exposure, especially in those patients with the hereditary form of the disease, who have elevated radiosensitivity.…”

Section: Correspondence Between Signal-void Spots On Mr Imaging and Cmentioning

confidence: 99%

Is CT Still Useful in the Study Protocol of Retinoblastoma?

Galluzzi¹,

Hadjistilianou²,

Cerase³

et al. 2009

AJNR Am J Neuroradiol

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“…Ultrasonography is a readily available and useful tool to evaluate intraocular disease and view the dynamic characteristics of lesions but its accuracy in identifying intraocular calcification is only 80%. Further, the presence of complex intraocular interfaces, such as those caused by vitreous opacities, retinal masses, subretinal fluid and retinal detachments, limits the usefulness of ultrasonography 23. CT is considered as the best imaging tool for detection of calcification and areas as small as 2 mm can be reliably detected 23.…”

Section: Discussionmentioning

confidence: 99%

“…Further, the presence of complex intraocular interfaces, such as those caused by vitreous opacities, retinal masses, subretinal fluid and retinal detachments, limits the usefulness of ultrasonography 23. CT is considered as the best imaging tool for detection of calcification and areas as small as 2 mm can be reliably detected 23. However, the superior soft tissue resolution of MRI over CT makes MRI a better modality for differentiating retinoblastoma from other simulating lesions 23.…”

Section: Discussionmentioning

confidence: 99%

“…CT is considered as the best imaging tool for detection of calcification and areas as small as 2 mm can be reliably detected 23. However, the superior soft tissue resolution of MRI over CT makes MRI a better modality for differentiating retinoblastoma from other simulating lesions 23. On T1-weighted MR images, retinoblastoma appears isointense to relatively hyper-intense relative to the vitreous while on T2-weighted images, it appears distinctly hypo-intense compared with the vitreous.…”

Section: Discussionmentioning

confidence: 99%

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