Nanoinformatics has recently emerged to address the need of computing
applications at the nano level. In this regard, the authors have participated in
various initiatives to identify its concepts, foundations and challenges. While
nanomaterials open up the possibility for developing new devices in many
industrial and scientific areas, they also offer breakthrough perspectives for
the prevention, diagnosis and treatment of diseases. In this paper, we analyze
the different aspects of nanoinformatics and suggest five research topics to
help catalyze new research and development in the area, particularly focused on
nanomedicine. We also encompass the use of informatics to further the biological
and clinical applications of basic research in nanoscience and nanotechnology,
and the related concept of an extended “nanotype” to coalesce
information related to nanoparticles. We suggest how nanoinformatics could
accelerate developments in nanomedicine, similarly to what happened with the
Human Genome and other –omics projects, on issues like exchanging
modeling and simulation methods and tools, linking toxicity information to
clinical and personal databases or developing new approaches for scientific
ontologies, among many others.