Medical interventions for traumatic hyphema

Woreta, Fasika A.; Lindsley, Kristina; Gharaibeh, Almutez; Ng, Sueko M; Scherer, Roberta W.

doi:10.1002/14651858.cd005431.pub5

Cited by 2 publications

(6 citation statements)

References 52 publications

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“…This study aims to investigate the risk factors associated with low vision in patients suffering from traumatic hyphema, providing critical insights that could guide clinical practices to prevent the condition and enhance patient prognosis Our ndings corroborate existing research, such as Simanjuntak et al [4] , showing that initial VA, timing of hospital visits, and the degree of hyphema are primary risk factors for low vision in patients with traumatic hyphema. Notably, the gender disparity observed aligns with prior studies, indicating a higher incidence rate among males (2.93:1), attributed to greater exposure to high-risk activities and occupations [5][6][7] . This gender-related trend is consistent with global data but varies signi cantly by region.…”

Section: Discussionsupporting

confidence: 84%

“…A retrospective study in Colombia showed that corticosteroids and mydriatics were effective in the treatment of traumatic hyphema above grade I [14] . However, in a meta-analysis published in 2023, researchers did not nd a signi cant improvement in visual acuity, and thought that patients treated with aminocaproic acid or tranexamic acid seemed to have less chance of rebleeding [5] . However, patients treated with aminocaproic acid took longer to absorb the accumulated blood [5] .…”

Section: Discussionmentioning

confidence: 99%

“…It is one of the serious and stubborn complications after ocular trauma, and is also one of the important risk factors for low vision after ocular trauma. The elevation of intraocular pressure secondary to hyphema is caused by red blood cells, platelets and brin blocking the trabecular meshwork or direct contusion of the aqueous humor discharge channel [5] . In this study, 38% of the patients had elevated intraocular pressure at admission and were diagnosed as secondary glaucoma, but the nal statistical results did not show that secondary glaucoma was signi cantly related to the nal visual acuity of the patients, which may be due to the timely control of intraocular pressure after admission.…”

Section: Discussionmentioning

confidence: 99%

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A retrospective study on risk factors for low vision in patients with traumatic hyphema

Hao,

Zhou,

Wang

et al. 2024

Preprint

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Background: This study examines the risk factors associated with low vision following traumatic hyphema to enhance prognosis evaluation. Methods: A retrospective analysis was performed on medical records of 58 patients diagnosed with traumatic hyphema at Tangdu Hospital, Air Force Medical University, from January 2017 to December 2022. Factors such as age, sex, cause of injury, time since injury, initial visual acuity, hyphema grade, intraocular pressure, and complications were evaluated using multivariate logistic regression with SPSS software. Results: The patient cohort was predominantly male (81%), with the majority of injuries occurring during occupational activities (38%). Other significant causes included altercations (19%), recreational activities (19%), traffic accidents (8.6%), sports injuries (8.6%), and fireworks (6.8%). Poor vision outcomes were primarily linked to vitreous hemorrhage, traumatic cataract, and iridodialysis, with significant risk factors being the time since injury, initial visual acuity, and hyphema grade. Conclusions: Traumatic hyphema is most common in males and frequently results from occupational incidents. The most critical predictors of adverse visual outcomes are the grade of hyphema, initial visual acuity, and elapsed time since injury, with initial visual acuity serving as an independent predictor of vision impairment. Trial registration: Not applicable. This retrospective study did not require trial registration.

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Section: Discussionsupporting

confidence: 84%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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A retrospective study on risk factors for low vision in patients with traumatic hyphema

Hao,

Zhou,

Wang

et al. 2024

Preprint

View full text Add to dashboard Cite

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“…To date, commonly accepted treatment modalities for hyphema consist of intensive monitoring, topical treatment for lowering intraocular pressure, mydriatics to prevent iris adhesions and topical corticosteroids to prevent associated inflammation. However, none of these interventions has been proven to be effective [ 9 ]. In refractory cases, surgical intervention is indicated to prevent serious irreversible complications such as corneal staining and secondary glaucoma [ 17 , 18 ].…”

Section: Discussionmentioning

confidence: 99%

“…Intraocular particles in the AH can also lead to obstruction of the trabecular meshwork (TM) and disruption of the primary drainage pathway, causing a rise in IOP and the development of SOAG [ 8 ]. Although there are medical and surgical treatments to deal with these particle-related complications [ 9 ], effective preventive measures are lacking.…”

Section: Introductionmentioning

confidence: 99%

Harnessing Standing Sound Waves to Treat Intraocular Blood Cell Accumulation

Kenigsberg,

Shperling,

Nagler-Avramovitz

et al. 2024

Micromachines

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Certain ocular conditions result from the non-physiological presence of intraocular particles, leading to visual impairment and potential long-term damage. This happens when the normally clear aqueous humor becomes less transparent, thus blocking the visual axis and by intraocular pressure elevation due to blockage of the trabecular meshwork, as seen in secondary open-angle glaucoma (SOAG). Some of these “particle-related pathologies” acquire ocular conditions like pigment dispersion syndrome, pseodoexfoliation and uveitis. Others are trauma-related, such as blood cell accumulation in hyphema. While medical and surgical treatments exist for SOAG, there is a notable absence of effective preventive measures. Consequently, the prevailing clinical approach predominantly adopts a “wait and see” strategy, wherein the focus lies on managing secondary complications and offers no treatment options for particulate matter disposal. We developed a new technique utilizing standing acoustic waves to trap and direct intraocular particles. By employing acoustic trapping at nodal regions and controlled movement of the acoustic transducer, we successfully directed these particles to specific locations within the angle. Here, we demonstrate control and movement of polystyrene (PS) particles to specific locations within an in vitro eye model, as well as blood cells in porcine eyes (ex vivo). The removal of particles from certain areas can facilitate the outflow of aqueous humor (AH) and help maintain optimal intraocular pressure (IOP) levels, resulting in a non-invasive tool for preventing secondary glaucoma. Furthermore, by controlling the location of trapped particles we can hasten the clearance of the AH and improve visual acuity and quality more effectively. This study represents a significant step towards the practical application of our technique in clinical use.

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Medical interventions for traumatic hyphema

Cited by 2 publications

References 52 publications

A retrospective study on risk factors for low vision in patients with traumatic hyphema

A retrospective study on risk factors for low vision in patients with traumatic hyphema

Harnessing Standing Sound Waves to Treat Intraocular Blood Cell Accumulation

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