Medical management of active chronic otitis media: A controlled study

Browning, George G.; Gatehouse, Stuart; Calder, I T

doi:10.1017/s0022215100105444

Cited by 71 publications

(38 citation statements)

References 8 publications

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“…This was a limitation as almost all our patients had admitted to have used such medications. But quite interestingly, some investigators have found little or no evidence that topical antibiotics can cause significant SNHL in humans [19].…”

Section: Discussionmentioning

confidence: 99%

Sensorineural Hearing Loss in Patients with Chronic Suppurative Otitis Media

Kolo

Salisu

Yaro

et al. 2011

Indian J Otolaryngol Head Neck Surg

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Even though there are other complications of chronic suppurative otitis media, the aspect of hearing loss is often studied. Nevertheless, the occurrence of sensorineural hearing loss in patients with this disease is still controversial. This study aim (1) to assess the association between sensorineural hearing loss and chronic suppurative otitis media, (2) to investigate some clinical factors that might affect the sensorineural component in patients with this disease. This was a retrospective analysis of the clinical records and pure tone audiograms of patients with chronic suppurative otitis media in a Nigerian Tertiary Health Institution from January 2003 to December 2008. Sixty-nine patients with a mean age of 28.93 years; standard deviation of 18.593 were studied. They had an age range of 4-73 years. The duration of otorrhea ranged from 2 months to 20 years; with a mean of 6.11 years (standard deviation of 6.393). The mean bone conduction threshold in the diseased ear was 39.07 dB (standard deviation of 12.028), and 10.26 dB (standard deviation of 2.620) in the control ear (P \ 0.05). The mean bone conduction threshold differences between the diseased and control ears range from 21.69 to 34.52 dB across the frequencies 0.5, 1.0, 2.0, and 4.0 kHz. These differences tended to increase with increasing frequency and were all significant (P \ 0.05). In the diseased ears, there were no significant correlation between the age, duration of otorrhea, and the degree of SNHL (r = 0.186, P [ 0.05; r = 0.190, P [ 0.05 respectively). Patients with chronic suppurative otitis media had a significant degree of sensorineural hearing loss in this study. The higher frequencies were more affected; however, the patient's age and duration of otorrhea seem not to have any correlation with the degree of sensorineural hearing loss.

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Section: Discussionmentioning

confidence: 99%

Sensorineural Hearing Loss in Patients with Chronic Suppurative Otitis Media

Kolo

Salisu

Yaro

et al. 2011

Indian J Otolaryngol Head Neck Surg

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“…Concerns have been expressed regarding the use of ear drops containing aminoglycosides and polymixins [64], but these may dramatically improve many cases of chronic otorrhoea which, if left untreated, may be prone to serious complications, including sensorineural deafness. The risk of ototoxicity appears to be very small [65] and MERFIELD et al [66] could find no evidence of sensori-neural hearing loss in 70 ears treated with drops containing potentially ototoxic drugs. The use of antibiotic drops combined with hydrocortisone is significantly more effective [67].…”

Section: Hospital Carementioning

confidence: 95%

Primary ciliary dyskinesia: diagnosis and standards of care

Bush¹,

Cole²,

Hariri³

et al. 1998

Eur Respir J

347

285

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Primary ciliary dyskinesia (PCD) is characterized by disease of the upper and lower respiratory tract, in association with visceral mirror image arrangement in 50% of cases, due to abnormal structure and/or function of cilia. The purpose of this paper is to review the clinical features, diagnosis and management of PCD. Presentations include neonatal respiratory distress, recurrent lower respiratory tract infection, chronic rhinosinusitis and male infertility. PCD enters the differential diagnosis of bronchiectasis, atypical asthma, and unusually severe upper airway disease. Diagnosis is by a cascade of investigations, starting with the saccharin test in patients older than 10 yrs; ciliary beat frequency and pattern on light microscopy; and electron microscopy to assess ciliary morphology and orientation. It is important not to confuse primary and secondary ciliary abnormalities. Nasal nitric oxide is low in PCD, and this measurement shows promise as a screening test for PCD. Diagnosis is important, in order to prevent the development of bronchiectasis and to avoid any unnecessary otorhinolaryngological procedures. Regular follow-up is essential, and management should be multidisciplinary, with input from centres with a special interest in PCD, having access to paediatric and adult chest physicians, otolaryngologists and audiological physicians, physiotherapists, counselling services and fertility clinics. The prognosis is good, but morbidity can be considerable if PCD is incorrectly managed.

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“…However, Browning et al found the incidence of CSOM to be 1.9% in males and 1.2% in females. 10 A sex ratio of 1.3 to 1 was found by M.A Yaor et al in their study. 11 In our study, 70% cases belonged to rural population while 30% belonged to urban population.…”

Section: Discussionmentioning

confidence: 55%

Factors Influencing Surgical Outcome of Myringoplasty in Tubotympanic Type of Chronic Otitis Media

Das¹,

Das²

2017

jemds

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BACKGROUNDChronic otitis media is an inflammatory process of the mucoperiosteal lining of the middle ear space and mastoid. Infection of the middle ear has been a problem encountered in the human race, and is as old as humanity itself. Chronic suppurative otitis media (CSOM) is one of the most common causes of ear infection in developing countries particularly in South-east Asian countries. Chronic middle ear disease is a major problem in India especially in the rural areas. It is estimated that 6% of Indian population suffers from chronic ear disease. The term "Tubotympanic disease" is sometimes used to describe COM with a central perforation. The two principal aims of management of tubotympanic chronic otitis media are the eradication of infection and improvement of hearing by the closure of the tympanic membrane perforation which can be achieved either conservatively or by surgery. The surgical treatment of CSOM is still controversial. Some surgeons advice only repair of central perforation of tympanic membrane in non-cholesteatomatous tubotympanic chronic otitis media using graft i.e. myringoplasty to achieve a dry ear with improved hearing. This study aims to determine the factors responsible for successful surgical outcome of myringoplasty. MATERIALS AND METHODSThis hospital-based prospective study was done in the Dept. of ENT, Assam Medical College and Hospital, Dibrugarh from 1 st January 2015 to 31 st December 2015 in diagnosed cases of tubotympanic variant of CSOM. Thirty patients were included in this study after fulfilling inclusion and exclusion criteria. The surgical outcomes were assessed in terms of hearing gain, graft uptake and dryness of ear. RESULTSThirty patients of tubotympanic type of CSOM reviewed in the study with mean age group of 35.16 + 12.75 years underwent myringoplasty. Successful graft uptake post-operatively at 3 rd followup (12 th week) was seen in 83.33%. Dry ear was achieved at the end of 12 th week in 86.67% and gain in hearing at 3 rd post-operative review was 9.90 + 1.81 dB. 5 cases had graft failure, 4 cases failed to achieve dry ear. Extremity of ages, lower socio-economic status, postoperative URTI and ET dysfunction, disease in contralateral ear were associated factors in determining graft uptake and dry ear. CONCLUSIONMyringoplasty has been established as a very effective surgical management of tubotympanic variant of CSOM. Success of myringoplasty can be measured in terms of gain in hearing, graft uptake and dry ear. Our study acknowledges that successful outcome of surgery is determined by a range of factors like lower socio-economic status particularly in rural population with unhygienic living conditions, presence of nidus of infection in the upper airway along with eustachian tube dysfunction, otitis externa, disease in contralateral ear may be considered as some of the possible factors responsible for influencing the outcomes of surgery in tubotympanic type of chronic otitis media. But we emphasised that more cases or study population for longer duration...

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Medical management of active chronic otitis media: A controlled study

Cited by 71 publications

References 8 publications

Sensorineural Hearing Loss in Patients with Chronic Suppurative Otitis Media

Sensorineural Hearing Loss in Patients with Chronic Suppurative Otitis Media

Primary ciliary dyskinesia: diagnosis and standards of care

Factors Influencing Surgical Outcome of Myringoplasty in Tubotympanic Type of Chronic Otitis Media

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