Medical treatment of type 2 diabetes mellitus: Recommendations of the Diabetes, Obesity and Nutrition Group of the Spanish Society of Internal Medicine

Consensus 2021 for medical management of type 2 diabetes from the diabetes, obesity, and nutrition working group of the Spanish Society of Internal Medicine

“…The first version of this consensus was published in 2020 in Revista Clínica Española (online, June 2020) 9 . This updated version contains additional information from four clinical trials and two systematic reviews [11][12][13][14][15][16][17] .…”

“…There are many national and international proposals for tackling T2D therapeutically which vary in complexity and applicability in daily clinical practice. To provide practical guidance on the choice of antidiabetic drugs, the diabetes, obesity, and Nutrition Working Group of the Spanish Society of Internal Medicine (Sociedad Española de Medicina Interna [SEMI]) published its recommendations in 2020 based on a critical review of the scientific literature 9 . This document updates those recommendations based on new findings published in 2020.…”

Management of Type 2 Diabetes Mellitus in Elderly Patients with Frailty and/or Sarcopenia

“…It is recommended to maintain a more conservative therapeutic approach in these elderly patients with sarcopenia and/or frailty since they do not benefit from strict glycemic control. This glycemic control should always be based on the patient’s functional status [ 29 ]. In these patients, who are usually affected by polypharmacy, treatment should be individualized and simplified to achieve better adherence.…”

Review of the algorithms used in exhaled breath analysis for the detection of diabetes

“…A different mechanism causes type 1 diabetes, in which the patient's body stops producing insulin due to the autoimmunology aggression on beta-cells [75,76]. The major difference from the patient perspective is that type 2 diabetes can be prevented, for example by appropriate prophylaxis, quitting smoking, changing diet, and incorporating physical activity [77], but at present there are no known methods of preventing type 1 diabetes [78]. Diabetes is manifested by hyperglycaemia, polyuria, polydipsia, weight loss (sometimes with polyphagia), and blurred vision.…”

“…The measured responses are commonly filtered, normalized [40,42,47,50,69,76,77], and preprocessed using baseline manipulation [57,94,118] and/or baseline subtraction [57-59, 94, 119]. Figures 5 and 6 show the baseline fitting and subtraction.…”