Medical Uses of Ion-Exchange Resins

Arnold, William P.

doi:10.1056/nejm195108302450905

Cited by 8 publications

(3 citation statements)

References 18 publications

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“…Medical application of ion exchange resins has followed a pattern similar to previous years (22,65,88,188,813). By far, the greatest attention has been directed toward sodium reduction therapy for the relief of a variety of edemic conditions (39, 75, 80, 101, 125, 126, 136, 144, 145, 184, %U, 225, 234, 245, 246, 287, 289, 393, 406).…”

Section: Medical Applicationsmentioning

confidence: 73%

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Ion Exchange

Kunin¹,

McGarvey²

1953

Ind. Eng. Chem.

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I he past year has revealed several important developments in the realm of ion exchange unit operation. These developments have included a pronounced interest in ion exchange in fields other than the classic water conditioning operations, water softening, and deionization.Of considerable interest and importance is the commercial activity in the synthesis and application of ion exchange membranes. This development may represent a revolutionary change in electrochemical operations. ANEXCELLENT review article has been prepared by Boyd (53) summarizing the newer theories of ion exchange. Cassidy (79) gave a detailed account of ion application for separation and purification processes. Several review articles have also appeared in the foreign literature ( 9

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Section: Medical Applicationsmentioning

confidence: 73%

“…4. The distances traveled are not too great (within 10 miles THE Rise of the Rubber Railroad" is not only the title of a very complete and accurate digest of the economic and engineering aspects of long overland conveyor systems (22), but it also aptly describes the direction and motivation of the belt conveyor industry today.…”

Section: Bulk-handling Conveyorsmentioning

confidence: 99%

Ion Exchange

Kunin¹,

McGarvey²

1953

Ind. Eng. Chem.

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“…The functional group such as amine is a part of the majority of bitter drugs which is responsible for the obnoxious taste of these drugs. To reduce the bitterness of such drugs, the complex formation can be induced with some suitable agent which can result in blocking of the functional group [7][8][9][10]. Normally the drugs are converted to estolates and stearates which is usually the process used for the formation of complexes but nowadays ion exchange resins can be used for the formation of such complexes.…”

Section: Introductionmentioning

confidence: 99%

Ion Exchange Resins for Clinical Applications

Sarfraz

2023

Ion Exchange Resins

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Ion exchange resins are the cross-linked polymers that are insoluble in water and consist of charged ionic groups, for exchanging counter-ions, at repeating positions along the resin. IERs are majorly classified into two types i.e., cationic exchange resins and anionic exchange resins, depending on the type of ion exchanged. Over the last few years, ion exchange resins have gained significant attention owing to their various benefits in drug formulations improving the taste, stability, anti-deliquescence, and dissolution of the drug. They also play a role in targeted drug delivery via employing various delivery technologies such as sigmoidal release system, gastric retentive system, hollow fiber system and microencapsulated resonates. Furthermore, they are also used for therapeutic purposes like treating different ailments and abnormalities such as treating high cholesterol, edema, pruritus, cardiac edema, uremia etc. The chapter presents an overview of the role of ion exchange resins in various clinical implications.

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Cardiovascular Diseases

Schaaf¹

1954

AMA Arch Intern Med

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It has been hypothesized that Helicobacter pylori (Hp) infection may contribute to reduced stature, risk of hypertension or obesity. The aim was to evaluate body indices in Hp positive and negative persons. A total of 2436 subjects (4-100 years old) were tested for Hp status by 13 C-urea breath test. Data on height and weight were collected for 84%, and blood pressure for 80% of the study subjects. The prevalence of Hp infection was 41.6%. The odds ratio for a 10-year increase in age was 1.21 (95% CI 1.17-1.25, p-value <0.001). Statistically significant negative association of Hp positivity with body height was most pronounced in the younger age groups, while a positive association of Hp positivity with body mass index was only seen in those aged 15+ years. There was a negative effect of Hp positivity on systolic and diastolic blood pressure in subjects below 25 and a relatively strong positive effect on blood pressure in subjects over 65 years. Residual confounding by social characteristics as a possible explanation for the associations of Hp positivity with height and blood pressure cannot be excluded. Unmeasured factors related to social and family environment may cause the apparent association between Hp positivity and children's growth and blood pressure.

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Medical Uses of Ion-Exchange Resins

Cited by 8 publications

References 18 publications

Ion Exchange

Ion Exchange

Ion Exchange Resins for Clinical Applications

Cardiovascular Diseases

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