Medicated gelfoam for the treatment of recalcitrant otomycosis

Dorasala, Surya Prakash; Dorasala, Srinivas

doi:10.4103/0971-7749.108155

Cited by 5 publications

(3 citation statements)

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“…Otomycosis, a fungal infection of the external auditory canal, is increasingly common in general practice and ENT clinics, accounting for up to 20% of ENT outpatient consultations in some regions (1,2). Fungi are believed to cause from 2 to 15% of cases of otitis externa (3)(4)(5).…”

Section: Introductionmentioning

confidence: 99%

Otomycosis - a review of current management trends

Boolaky,

Sandooram

2024

Preprint

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Otomycosis is increasing in prevalence and can account for up to 20% of ENT outpatient consultations in warm and humid regions. Objectives: The aim of this review was to investigate the treatment strategies and antifungal agents used in various institutions and to highlight current trends. Design: PubMed, Cochrane Library and Google Scholar electronic databases were searched for freely-accessible articles spanning January 2001 and December 2020. Results: 59 full-text English-language articles were retrieved. Aspergillus spp. were the commonest species isolated followed by Candida spp. Clotrimazole-resistant Aspergillus spp. were encountered more frequently among immunosuppressed patients. Topical medications included drops, creams, ointments, powders, lotions and sprays. Systemic treatment was given orally or intravenously. Antifungal agents used were azoles, polyenes, echinocandin, allylamine, thiocarbamate, hydroxyquinoline and griseofulvin. Antiseptics employed included Betadine, Gentian Violet, N-chlorotaurine, Castellani’s Paint, Cresylate drops and Tincture Merthiolate. Steroids (beclomethasone, betamethasone, dexamethasone and hydrocortisone) were generally used in combination therapy. Acidifying agents administered were 3% boric acid, 2% acetic acid and 2% salicylic acid. Lignocaine and tetracaine formed part of some formulations. Conclusions: Topical applications are the mainstay of treatment of otomycosis, but occasionally oral or intravenous agents are required. Aural toilet and specific antiseptics have an important role. Clotrimazole remains an essential antifungal against a variety of fungi, but other antifungals may be needed against resistant species and in immunocompromised patients.

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Section: Introductionmentioning

confidence: 99%

Otomycosis - a review of current management trends

Boolaky,

Sandooram

2024

Preprint

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“…It has been found that otitis externa (OE) constitutes about 5-20% of ear consultations to otorhinolaryngologists; the majority of these cases are caused by bacteria and in 9-25% fungal agents are the cause and the microorganisms which attribute for these clinical conditions are present as saprobes in nature [9][10][11]. Otomycosis can be presented with non-specific manifestations such as itching, discomfort and otalgia, aural fullness, tinnitus decrease in hearing and otorrhea [12][13][14][15]. There are many factors which may take important roles in fungal infection of the ear like humidity moisture Warmth, darkness and water access into the external auditory canal during bathing decreased immune function, preexisting ear diseases, cleaning of ear wax, and comorbid conditions such as diabetes and dermatological diseases [16][17][18][19].…”

Section: Introductionmentioning

confidence: 99%

Presentation Pattern and Fungal Agents Spectrum Causing Otommycosis

Dekhil

2018

Asian J Pharm Clin Res

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Objective: This study was aimed to identify the public pattern of presentation, influencing factors, and sort the fungal species, distribution of sex of patients with otomycosis.Results: The predominant complaints were pruritus and found in 76 patients (88.73%), discomfort and pain found in 62 patients (72.09%), aural fullness in 48 patients (55.81%), tinnitus in 34 patients (39.53%), hearing impairment in 50 cases (58.31%), ear discharge in 22 patients (25.58%), and most of the symptoms seen in 36 patients (68.14%). The results showed a total of eight fungal species belong to six different genera, namely, Aspergillus, Candida, Penicillium, Rhizopus, Alternaria, and Cephalosporium were isolated during this study. Among identified fungi, Aspergillus niger was found to be the most prevalent fungal species with 35.71% followed by Candida albicans (27.55%), Aspergillus flavus (10.20%), Aspergillus fumigatus (8.16), Penicillium digitatum (6.12%) and Cephalosporium species (4.08%), and Rhizopus species (5.1%), while Alternaria alternata had the lowest percentage (6.54%).Conclusion: Otomycosis/mycotic otitis externa is still a common problem and there is a rise in the occurrence of otomycosis in latest years, especially in tropical and subtropical humid climates.

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Section: Introductionmentioning

confidence: 99%

Presentation Pattern and Fungal Agents Spectrum Causing Otommycosis

Dekhil

2018

Asian J Pharm Clin Res

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Objective: This study was aimed to identify the pattern of presentation, influencing factors, and sort of the fungal species, distribution of sex of patients with otomycosis. Methods:Eighty-six patients attended to Ad-Diwaniyah teaching hospital, Iraq were screened for identification of fungi causing otomycosis from October 2014 to November 2015. 50 patients were females while 36 patients were males. 12 patients of the total number were with bilateral involvement. Diabetes mellitus, leukemia, chemotherapy, and chemoradiation were the associated systemic diseases which were recorded in patients with otomycosis and diabetes mellitus was detected in 53.84% of patients with systemic diseases. Results:The predominant complaints were pruritus and found in 76 patients (88.73%), discomfort and pain found in 62 patients (72.09%), aural fullness in 48 patients (55.81%), tinnitus in 34 patients (39.53%), hearing impairment in 50 cases (58.31%), ear discharge in 22 patients (25.58%), and most of the symptoms seen in 36 patients (68.14%). The results showed a total of eight fungal species belong to six different genera, namely, Aspergillus, Candida, Penicillium, Rhizopus, Alternaria, and Cephalosporium were isolated during this study. Among identified fungi, Aspergillus niger was found to be the most prevalent fungal species with 35.71% followed by Candida albicans (27.55%), Aspergillus flavus (10.20%), Aspergillus fumigatus (8.16), Penicillium digitatum (6.12%) and Cephalosporium species (4.08%), and Rhizopus species (5.1%), while Alternaria alternata had the lowest percentage (6.54%). Conclusion:Otomycosis/mycotic otitis externa is still a common problem and there is a rise in the occurrence of otomycosis in latest years, especially in tropical and subtropical humid climates.

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Medicated gelfoam for the treatment of recalcitrant otomycosis

Cited by 5 publications

References 1 publication

Otomycosis - a review of current management trends

Otomycosis - a review of current management trends

Presentation Pattern and Fungal Agents Spectrum Causing Otommycosis

Presentation Pattern and Fungal Agents Spectrum Causing Otommycosis

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