Medication Adherence and Drug Attitude Amongst Male Patients with the Methamphetamine-Induced Psychotic Disorder After Discharge: A Three Months Follow Up Study

Asadi, Mohammad; Rashedi, Vahid; Khademoreza, Nooshin; Seddigh, Ruohollah; Keshavarz-Akhlaghi, Amir-Abbas; Ahmadkhaniha, Hamid Reza; Rezvaniardestani, Seied-Mohamadhosein; Lotfi, Ahmad; Shalbafan, Mohammadreza

doi:10.1080/02791072.2021.1883778

Cited by 7 publications

(5 citation statements)

References 28 publications

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“…It‘s lower than the percentage with the same scales, DAI-10 and MPR, among some other psychiatric patients. Asadi et al reported that more than 85% of participants had positive attitudes toward medication and more than 55% had good medication adherence among Iranian male patients with methamphetamine-induced psychotic disorder in a three-month follow-up study after discharge from a mental hospital ( 22 ).…”

Section: Discussionmentioning

confidence: 99%

“…Based on MPR, more than 80% equal good adherence, 50–80% equal partial adherence, and less than 50% equal poor adherence. In our study last month, the MPR represents the proportion of days of medication supply in a specified period and is given by the sum of days divided by the number of days within the time interval ( 22 , 23 ). In addition, based on the participant‘s report and documented visits for psychotherapy sessions, the psychotherapy adherence of the patients was evaluated.…”

Section: Methodsmentioning

confidence: 99%

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Factors associated with pharmacological and psychotherapy treatments adherence in patients with borderline personality disorder

Mohammadabadi

Mohammadsadeghi²,

Adrebili³

et al. 2022

Front. Psychiatry

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BackgroundBorderline personality disorder is a major mental illness characterized by sustained relationship instability, impulsive behavior, and intense affects. Adherence is a complex behavior, from minor refusals to abandonment of treatment, which can be affected by various factors. Therefore, the present study aimed to investigate the factors affecting pharmacological and psychotherapy adherence, patients' attitude toward medication, and assessing medication and treatment adherence in patients with borderline personality disorder referred to an outpatient referral clinic in Tehran, Iran.MethodsThe study was a cross-sectional study. The files of patients with borderline personality disorder referred to the outpatient clinic of the Tehran Psychiatric Institute were reviewed as the first step. Data were collected using the Drug Attitude Inventory-10 (DAI-10) questionnaire and a questionnaire to determine the attitude of patients toward pharmacological and psychotherapy treatment as well as therapeutic adherence. After collecting data, patients' therapeutic adherence was divided into poor, partial, and good compliance.ResultsNinety-four patients were involved in the study, and fifty-four were women. Findings of DAI showed that 54 (57.4%) participants had negative attitudes toward medication, while 38 (40.4%) participants showed a negative attitude toward psychotherapy treatment. Additionally, the percentage of patients with good psychotherapy adherence (44.7%) was higher than that of patients with good medication adherence (31.9%). The most common reasons for discontinuation of treatment were medication side effects (53.1%), dissatisfaction with the therapist (40.3%), and then fear of medication dependence (40%). Patients with higher education levels and a positive history of hospitalization in a psychiatric ward had better adherence to psychotherapy (P < 0.05).ConclusionResults of the current study show that attitude toward psychotherapy is more favorable than pharmacotherapy among patients with BPD. The rationale may be that medications are mainly prescribed for comorbid conditions and do not have substantial effects on the BPD symptoms, resulting in low medication adherence.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Factors associated with pharmacological and psychotherapy treatments adherence in patients with borderline personality disorder

Mohammadabadi

Mohammadsadeghi²,

Adrebili³

et al. 2022

Front. Psychiatry

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“…The rst questionnaire, was DAI-10 based that evaluate attitude of patients toward medication with 10 yes-no questions and higher total score between +10 and -10 shows more positive attitude. Shariati et al con rmed psychometric properties of the Persian version of the scale (19). They reported Test-retest reliability was 0.805 and Cronbach's α 0.787.…”

Section: Instrumentsmentioning

confidence: 97%

Factors associated with pharmacological and non-pharmacological treatments adherence in patients with Borderline personality disorder in Iran

Shalbafan

Mohammadabadi

Mohammadsadeghi

et al. 2022

Preprint

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BackgroundBorderline personality disorder is a major mental illness characterized by a sustained relationship instability, impulsive behavior and intense affects. Adherence is a complex behavior, from minor refusals of treatment to inappropriate use of health services or even abandonment of treatment, which can be affected by various factors. Therefore, the present study aimed to investigate the factors affecting pharmacological and non-pharmacological adherence in patients with borderline personality disorder referred to an outpatient referral clinic in Tehran, Iran.MethodsThe study was a retrospective cohort. The files of patients with borderline personality disorder referred to the outpatient clinic of the Tehran Psychiatric Institute were reviewed as the first step. In the next step, we contacted the patients and asked them to fill out the questionnaires. Data were collected using the Drug Attitude Inventory (DAI) questionnaire and a researcher made questionnaire to determine the attitude of patients toward pharmacological and non-pharmacological treatment and therapeutic adherence. After collecting data, patients’ therapeutic acceptance was divided into three groups: poor, partial, good compliance. The data were analyzed by SPSS software version-22.Results Ninety-four patients were involved in the study and fifty four of them were women. In terms of psychotherapy adherence, patients with higher education and hospital admission history have better compliance. Medication attitudes were negative in 54 patients (57.4%), while 40.4% of them stated that psychotherapy or counselling did not help their condition and showed a negative attitude toward non-pharmacological treatment. Additionally, psychotherapy good adherence of the patients (44.7%) was higher than medication good adherence (31.9%). The most common reasons for discontinuation of treatment were medication side effects (53.1%), dissatisfaction with the therapist (40.3%) and then fear of medication dependence (40%). The results showed no relationship between other demographic factors and treatment adherence.ConclusionsResults of the current study show that attitude toward psychotherapy is more positive than pharmacotherapy. In addition, according to the results, working on changeable factors such as patients’ fear of dependence to medication, dissatisfaction with the therapist, and medication side effects may improve patients' treatment adherence.

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“…Lack of approved specific effective treatments and non-adherence issues for the disorder might have negative consequences for the patient and significant others. 11 In a recent study from 2 different rehabilitation centers investigating treatment drop-outs and METH-negative urine result rates, it was found that 25% of participants showed METHabstinence at 12 months after residential treatment. 12 There has been a powerful emphasis on the fact that continuing abstinence declines over time with early periods of abstinence 2 Substance Abuse: Research and Treatment (especially first 24 weeks of treatment) predicting later and continuing abstinence.…”

Section: Introductionmentioning

confidence: 99%

A 6-Month Follow-Up Study: Cognitive Impairment May Predict More Frequent Use of Methamphetamine

Karabulut¹

2023

Subst�Abuse

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Objectives: Methamphetamine (METH) use has been associated with impairments in a variety of cognitive functions. In this study, it was aimed to assess the relation between cognitive measures and frequency of METH use. Methods: Ninety-eight participants with methamphetamine use disorder were assessed with Wisconsin Card Sorting Test (WCST), Victoria-Stroop Word Color Test (SWCT), Trail Making Test (TMT) A and B. Participants were followed up during 6-month period with multiple urine toxicology tests (at baseline, month 1, month 2, month 3 and month 6). Results: Participants who had their prescriptions regularly were more likely to have higher rates of METH-negative urine results ( P = .003). Participants who had more correct numbers, completed more categories and had more conceptual level responses on WCST were more likely to use lower frequency of METH (OR = 0.006, P < .01; OR = 0.171, P < .001; OR = 0.024, P < .001; respectively). The higher error numbers and perseverative error rates on WCST were associated with more frequent METH use (OR = 0.023, P < .001; OR = 0.076, P < .001). Interference factor on SWCT was related with lower frequency of METH use whereas color naming factor on SWCT was related with higher rates of urine results (OR = 0.012, P < .001; OR = 3.628, P < .001; respectively). Higher TMT B-A score was related with more frequent METH use, although the significance disappeared after adjustment (OR = 0.002, P < .001). Having psychotic symptoms predicted less frequent use, but after adjustment for other significant variables, there was no significance. Conclusion: Lower frequency of METH use in the follow-up could be predicted by neurocognitive assessments. Deficits in executive functions, attention, set-shifting and mental flexibility seems to be the most effected domains and this effect may be independent from the severity of psychotic symptoms.

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Medication Adherence and Drug Attitude Amongst Male Patients with the Methamphetamine-Induced Psychotic Disorder After Discharge: A Three Months Follow Up Study

Cited by 7 publications

References 28 publications

Factors associated with pharmacological and psychotherapy treatments adherence in patients with borderline personality disorder

Factors associated with pharmacological and psychotherapy treatments adherence in patients with borderline personality disorder

Factors associated with pharmacological and non-pharmacological treatments adherence in patients with Borderline personality disorder in Iran

A 6-Month Follow-Up Study: Cognitive Impairment May Predict More Frequent Use of Methamphetamine

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