2013
DOI: 10.1542/peds.2013-1451
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Medication Adherence and Health Care Utilization in Pediatric Chronic Illness: A Systematic Review

Abstract: BACKGROUND AND OBJECTIVE: Advanced understanding of modifiable predictors of health care use in pediatric chronic illness is critical to reducing health care costs. We examined the relationship between medication non-adherence and health care use in children and adolescents who have a chronic medical condition. METHODS:A systematic review of articles by using PubMed, PsycINFO, and CINAHL was conducted. Additional studies were identified by searching reference sections of relevant manuscripts. Studies that test… Show more

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Cited by 196 publications
(140 citation statements)
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“…Our inclusion of medication nonadherence as a medication-related reason for an ED visit is unique, and reflects our belief that this should be included in estimates of the burden of MRVs. McGrady and Hommel 63 recently reported the significant impact of medication nonadherence and the related increased health care use in children and adolescents who have a chronic medical condition.…”
Section: Discussionmentioning
confidence: 99%
“…Our inclusion of medication nonadherence as a medication-related reason for an ED visit is unique, and reflects our belief that this should be included in estimates of the burden of MRVs. McGrady and Hommel 63 recently reported the significant impact of medication nonadherence and the related increased health care use in children and adolescents who have a chronic medical condition.…”
Section: Discussionmentioning
confidence: 99%
“…Nonadherence to prescribed treatment regimens is a major concern in the management of all chronic pediatric illnesses (11,12). However, there has been little investigation of the role that nonadherence plays in the outcomes of children with CKD (20).…”
Section: Discussionmentioning
confidence: 99%
“…Medication nonadherence is highly prevalent and negatively affects outcomes in patients with chronic childhood medical conditions (11,12), including dialysis patients (13)(14)(15) and kidney transplant recipients (16,17). Treatment of patients with CKD includes multiple medications, high dosing frequency, numerous dose adjustments due to disease progression, and the need for coordination of medication administration timing with meals, all of which create a unique context for medication nonadherence in children (18)(19)(20)(21).…”
Section: Introductionmentioning
confidence: 99%
“…The patients are primarily urban minorities (97% nonwhite), and 71% are insured by Medicaid or a Medicaid managed care organization (MCO), characteristics associated with more severe asthma. [8][9][10] The ward has 30 beds and is staffed by an attending, 2 residents, and 4 interns. Residents rotate in 4-week blocks.…”
Section: Settingmentioning
confidence: 99%