Medication Adherence and Its Association With Quality of Life Among Hypertensive Patients Attending Primary Health Care Centers in Saudi Arabia

Alsaqabi, Yasir S.; Rabbani, Unaib

doi:10.7759/cureus.11853

Cited by 7 publications

(8 citation statements)

References 22 publications

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“…In contrast to our findings, a study conducted in Spain found no relationship between polypharmacy and adherence [15]. On the other hand, a study in Saudi Arabia reported findings similar to ours regarding a relationship that exists between polypharmacy and level of adherence [12]. Family physicians can play an important role in increasing medication adherence among patients having comorbidities with polypharmacy by prescribing the most appropriate medications and avoiding those that are unnecessary.…”

Section: Identification Of Patient Characteristics and Other Factors ...contrasting

confidence: 88%

“…The global rate of poor adherence is 46.6% [11]. A study on adherence to hypertension medication in Alsaqabi, Saudi Arabia, found that 38.8% of patients did not adhere to the prescribed medication regimen [12]. Another factor that may contribute to nonadherence is a lack of social support, having someone to talk to or ask for help, such as a family member, friend, or neighbor [13].…”

Section: Introductionmentioning

confidence: 99%

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Medication Adherence Among Multimorbid Patients With Polypharmacy and Its Relation to Social Support at National Guard Primary Health Care Centers, Riyadh

Almutairi¹,

Alhazmi²,

Alotaibi³

et al. 2022

Cureus

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Objective: The aim of the present study was to estimate the prevalence of nonadherence to medication in multimorbid patients with polypharmacy and its relationship to social support in primary healthcare centers in Riyadh, Saudi Arabia.Methods: We conducted a cross-sectional, convenience-sample, non-randomized study in three primary healthcare centers managed by National Guard Health Affairs. The participants included 417 adult patients -(a) with two or more chronic illnesses and (b) who were taking two or more medications. The primary outcome variable was the prevalence of medication nonadherence in multimorbid patients with polypharmacy as measured by the modified Morisky Medication Adherence Scale (MMAS-8) . The second main variable was the impact of functional social support, as measured by the Duke-UNC Functional Social Support Questionnaire (FSSQ), on medication adherence.Results: The level of medication adherence was low for 194 (46.5%) of the 417 patients, medium for 127 (30.5%), and high for 96 (23%). There were 256 (61.4%) male participants and 161 (38.6%) females, and their mean age was 59.15 (SD ± 11.186) years. Additionally, 171 (41%) participants used two or three medications, 127 (30.5%) used four or five medications, and 119 (28.5%) used more than five medications; 178 (42.7%) of the patients had two comorbidities, 136 (32.9%) had three comorbidities, 69 (16.5%) had four comorbidities, and 31 (7.5%) had five comorbidities. Some social support data from the Duke-UNC Functional Social Support Questionnaire (FSSQ) was missing for 58 (13.9%) of the participants. Among the rest of the sample, reported levels of social support levels were high for 246 (59%) patients, medium for 101 (24.2%), and low for 12 (2.9%) patients. None of the differences between social support and medication adherence were statistically significant. However, 61 (24.8%) patients reported both high social support and high medication adherence; 173 (48.2%) had low social support and low medication adherence (p = 0.470). Conclusion:We found that medication nonadherence in multimorbid patients with polypharmacy was high (46.5%). Although there were no statistically significant relationships between social support and medication adherence, certain patient characteristics were associated with low medication adherence -age over 60 years, male gender, and number of medications.

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Section: Identification Of Patient Characteristics and Other Factors ...contrasting

confidence: 88%

Section: Introductionmentioning

confidence: 99%

Medication Adherence Among Multimorbid Patients With Polypharmacy and Its Relation to Social Support at National Guard Primary Health Care Centers, Riyadh

Almutairi¹,

Alhazmi²,

Alotaibi³

et al. 2022

Cureus

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“…Lower HRQoL affects medication adherence, which is important for managing hypertension (Holt et al, 2010 ). Overall, poor HRQoL is related to severe hypertension (Alsaqabi & Rabbani, 2020 ). The bidirectional associations between hypertension and HRQoL may lead to a vicious cycle.…”

Section: Discussionmentioning

confidence: 99%

“…Particularly, adherence to antihypertensive medications is essential for reducing blood pressure levels (Muntner et al, 2022 ). Uncontrolled hypertension is associated with nonadherence to the medication, such as improper dosage or frequency of medication (Alsaqabi & Rabbani, 2020 ). Low adherence to antihypertensive medication is a noteworthy barrier in managing hypertension (Holt et al, 2010 ).…”

Section: Introductionmentioning

confidence: 99%

Association between health‐related quality of life and nonadherence to antihypertensive medication

Kim

2023

Nursing Open

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Aim We aimed to examine the association between nonadherence to antihypertensive medications and Health‐related quality of life. Design A cross‐sectional survey was undertaken. Methods This study was conducted using the data from the Korea National Health and Nutrition Examination Survey. A total of 6493 participants who diagnosed with hypertension, affected by hypertension at the time of survey, and took daily antihypertensive medications or never took this medication were included. Multiple logistic regression analysis was performed to determine the factors that influenced the patients' nonadherence to antihypertensive medications according to sex. Results Our results showed that anxiety/depression was positively associated with antihypertensive medication nonadherence, regardless of sex. According to sex, mobility was negatively associated with antihypertensive medication nonadherence in women. In men, living together was negatively related to antihypertensive medication nonadherence. This study showed the factors associated with antihypertensive medication nonadherence according to sex. HRQoL was associated with antihypertensive medication nonadherence.

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“…4 Poor medication adherence among NCD patients has been consistently associated with poor perceived overall quality of life (QOL) and poor satisfaction with health. [5][6][7][8] The WHO framework on adherence to long-term therapies identifies several factors that can influence adherence, including social and economic factors, the health-care team/system, the characteristics of the disease and disease therapies, and patient-related factors. 4 There are various ways to measure medication adherence, including self-report methods (e.g., scales like the Morisky Medication Adherence Scale and Visual Analogue Scale), electronic medication monitoring, pill count, electronic medical records, pharmacy claims, and prescription refill records.…”

mentioning

confidence: 99%

Medication Adherence among Primary Care Patients with Common Mental Disorders and Chronic Medical Conditions in Rural India

Salazar

Srinivasan²,

Heylen

2023

Indian Journal of Psychological Medicine

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Background: Only a few studies have explored the relationship between psychosocial factors and medication adherence in Indian patients with noncommunicable diseases (NCDs). We aimed to examine the association of psychosocial variables with medication adherence in people with NCDs and comorbid common mental disorders (CMDs) from primary care in rural southern India. Methods: We performed a secondary analysis using baseline data from a randomized controlled trial in 49 primary care health centers in rural southern India (HOPE study). Participants were adults (≥30 years) with NCDs that included hypertension, diabetes, and/or ischemic heart disease, and comorbid depression or anxiety disorders. Medication adherence was assessed by asking participants if they had missed any prescribed NCD medication in the past month. Data were collected between May 2015 and November 2018. The association between psychosocial and demographic variables and medication nonadherence were assessed via logistic regression analyses. Results: Of the 2486 participants enrolled, almost one-fifth (18.06%) reported missing medication. Male sex (OR = 1.74, 95% CI 1.37–2.22) and higher internalized mental illness stigma (OR = 1.46, 95% CI 1.07–2.00) were associated with higher odds of missing medication. Older age (OR = 0.40, 95% CI 0.26–0.60, for participants aged 64–75 years vs 30–44 years), reporting more social support (OR = 0.65, 95% CI 0.49–0.86), and higher satisfaction with health (OR = 0.74, 95% CI 0.61–0.89) were associated with lower odds of missing medication. Conclusions: Greater internalized mental illness stigma and less social support are significantly associated with lower rates of medication adherence in patients with NCDs and comorbid CMDs in rural India.

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Medication Adherence and Its Association With Quality of Life Among Hypertensive Patients Attending Primary Health Care Centers in Saudi Arabia

Cited by 7 publications

References 22 publications

Medication Adherence Among Multimorbid Patients With Polypharmacy and Its Relation to Social Support at National Guard Primary Health Care Centers, Riyadh

Medication Adherence Among Multimorbid Patients With Polypharmacy and Its Relation to Social Support at National Guard Primary Health Care Centers, Riyadh

Association between health‐related quality of life and nonadherence to antihypertensive medication

Medication Adherence among Primary Care Patients with Common Mental Disorders and Chronic Medical Conditions in Rural India

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