Medication Adherence in HIV-Infected Smokers: The Mediating Role of Depressive Symptoms

Webb, Monica S.; Vanable, Peter A.; Carey, Michael P.; Blair, Donald C.

doi:10.1521/aeap.2009.21.3_supp.94

Cited by 61 publications

(44 citation statements)

References 57 publications

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“…The study assessed viral load, CD4+ count, cigarette smoking, and the past week and 3-month medication adherence. 68 The study found that 70% of participants smoked at least one cigarette per day, and smoking was associated with poorer past week and 3-month medication adherence. 3 In a study of HIV-positive men and women (n = 64), current cigarette smoking, lower CD4 counts and lower educational status emerged as independent predictors of poorer adherence among patients on HAART.…”

Section: Association Between Smoking and Increased Disease Activity Imentioning

confidence: 93%

Hydroxychloroquine and smoking in patients with cutaneous lupus erythematosus

Ezra

Jorizzo

2012

Clinical and Experimental Dermatology

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SummaryAntimalarials, such as chloroquine and hydroxychloroquine, have been used to treat cutaneous and systemic lupus erythematosus for decades with excellent therapeutic efficacy. Smoking seems to inhibit the therapeutic efficacy of antimalarials when treating cutaneous lupus erythematosus (CLE), but the reason behind this observation is unclear. In addition, antimalarials have been associated with several potentially serious adverse effects, including irreversible loss of vision. The aim of this literature review is to discuss the evidence for how cigarette smoking interferes with antimalarial efficacy in the treatment of CLE. Evidence-based data with long-term follow-up will allow determination of the aetiology for diminished antimalarial response, and enable selection of the best treatment to maximize long-term remission in CLE.

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Section: Association Between Smoking and Increased Disease Activity Imentioning

confidence: 93%

Hydroxychloroquine and smoking in patients with cutaneous lupus erythematosus

Ezra

Jorizzo

2012

Clinical and Experimental Dermatology

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“…Smoking during pregnancy is associated with a threefold increase in the risk of vertical HIV transmission [49]. Smoking is also correlated with lower drug adherence [50].…”

Section: Impact Of Continued Smokingmentioning

confidence: 99%

Smoking Cessation in Long-Term Conditions: Is There “An Opportunity in Every Difficulty”?

Siddiqi

Dogar

Siddiqi

2013

International Journal of Population Research

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Introduction. Smoking plays a causal role in several long-term conditions and worsens their outcomes. Focusing on six such conditions, we present a narrative review of seminal studies on the prevalence and impact of continued tobacco use on these conditions; the effectiveness of cessation interventions; the extent to which patients receive these interventions, and barriers to providing and taking up these interventions. Methods. A conceptual framework was used to identify questions for a series of focused literature reviews. Findings were synthesized and the literature was examined to identify themes common across these conditions. Results. Smoking prevalence is either similar or higher in patients with established long-term conditions compared to the general population. Continued smoking accelerates disease progression, worsens outcomes, and risks poor treatment compliance or further complications. There is strong evidence for the effectiveness of cessation interventions in achieving smoking abstinence. Despite this, only a small proportion of patients receive such interventions. Important barriers to uptake include concerns about weight management and drug safety, higher nicotine dependency and codependency, comorbidity, and misperceptions about the benefits of cessation. Conclusion. The benefits of offering smoking cessation in patients with long-term conditions are far too great for it to remain of a low priority.

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“…Smoking can be a response to negative feelings and mood states (Feldner, Babson, & Zvolensky, 2007;Reynolds, Neidig, & Wewers, 2004), and depression has been linked to smoking in an HIV-positive sample (Webb, Vanable, Carey, & Blair, 2009). Furthermore, psychological stresses associated with military training and deployment have been cited by soldiers as a motivation to smoke (Nelson et al, 2009;Stein et al, 2008).…”

Section: Original Investigation Present and Past Influences On Currenmentioning

confidence: 99%