Medication adherence monitoring using modern technology

Aldeer, Murtadha; Martin, Richard P.

doi:10.1109/uemcon.2017.8249101

Cited by 15 publications

(17 citation statements)

References 52 publications

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“…The size and storage capacity vary among the different types of available electronic pill boxes or bags. Most of the identified electronic pill boxes or bags possessed the ability to transmit patient medication adherence data in real time via existing cellular networks [ 1 , 9 , 26 - 28 , 38 - 43 , 100 ], wireless Bluetooth [ 1 , 44 , 45 ], or general packet radio service [ 27 , 46 , 101 , 102 ]. One device required manual uploading of patient adherence data during clinic visits [ 47 ].…”

Section: Resultsmentioning

confidence: 99%

“…Although the capability of these devices to store multiple medications makes them better suited for complex multidrug regimens, this advantage is dependent on the device, as they can vary drastically in size and pill storage capacity. This was evident when examining the Wisepill device’s storage capacity of 60 small-sized pills [ 1 , 27 , 39 , 41 , 46 ] compared with MedTracker’s storage capacity of a week’s worth of medication [ 44 ]. However, larger-sized devices are often described as obtrusive [ 10 , 40 , 48 ] and have increased risks to patient privacy [ 1 , 39 , 40 , 49 ], thus limiting the acceptability of the device for patient populations, particularly for those who do not wish to disclose their health status (eg, HIV positive) to others [ 39 ].…”

Section: Resultsmentioning

confidence: 99%

“…However, larger-sized devices are often described as obtrusive [ 10 , 40 , 48 ] and have increased risks to patient privacy [ 1 , 39 , 40 , 49 ], thus limiting the acceptability of the device for patient populations, particularly for those who do not wish to disclose their health status (eg, HIV positive) to others [ 39 ]. Furthermore, these devices cannot directly confirm ingestion of medications, raising concerns toward their medication adherence monitoring accuracy because potential patient behaviors, including pocket dosing and curiosity events , may impede medication adherence rate estimates [ 1 , 10 , 15 , 16 , 26 , 27 , 30 , 38 - 40 , 44 , 48 - 50 , 101 ]…”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Technologies for Medication Adherence Monitoring and Technology Assessment Criteria: Narrative Review

Mason¹,

Cho²,

Rayo³

et al. 2022

JMIR Mhealth Uhealth

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Background Accurate measurement and monitoring of patient medication adherence is a global challenge because of the absence of gold standard methods for adherence measurement. Recent attention has been directed toward the adoption of technologies for medication adherence monitoring, as they provide the opportunity for continuous tracking of individual medication adherence behavior. However, current medication adherence monitoring technologies vary according to their technical features and data capture methods, leading to differences in their respective advantages and limitations. Overall, appropriate criteria to guide the assessment of medication adherence monitoring technologies for optimal adoption and use are lacking. Objective This study aims to provide a narrative review of current medication adherence monitoring technologies and propose a set of technology assessment criteria to support technology development and adoption. Methods A literature search was conducted on PubMed, Scopus, CINAHL, and ProQuest Technology Collection (2010-present) using the combination of keywords medication adherence, measurement technology, and monitoring technology. The selection focused on studies related to medication adherence monitoring technology and its development and use. The technological features, data capture methods, and potential advantages and limitations of the identified technology applications were extracted. Methods for using data for adherence monitoring were also identified. Common recurring elements were synthesized as potential technology assessment criteria. Results Of the 3865 articles retrieved, 98 (2.54%) were included in the final review, which reported a variety of technology applications for monitoring medication adherence, including electronic pill bottles or boxes, ingestible sensors, electronic medication management systems, blister pack technology, patient self-report technology, video-based technology, and motion sensor technology. Technical features varied by technology type, with common expectations for using these technologies to accurately monitor medication adherence and increase adoption in patients’ daily lives owing to their unobtrusiveness and convenience of use. Most technologies were able to provide real-time monitoring of medication-taking behaviors but relied on proxy measures of medication adherence. Successful implementation of these technologies in clinical settings has rarely been reported. In all, 28 technology assessment criteria were identified and organized into the following five categories: development information, technology features, adherence to data collection and management, feasibility and implementation, and acceptability and usability. Conclusions This narrative review summarizes the technical features, data capture methods, and various advantages and limitations of medication adherence monitoring technology reported in the literature and the proposed criteria for assessing medication adherence monitoring technologies. This collection of assessment criteria can be a useful tool to guide the development and selection of relevant technologies, facilitating the optimal adoption and effective use of technology to improve medication adherence outcomes. Future studies are needed to further validate the medication adherence monitoring technology assessment criteria and construct an appropriate technology assessment framework.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Technologies for Medication Adherence Monitoring and Technology Assessment Criteria: Narrative Review

Mason¹,

Cho²,

Rayo³

et al. 2022

JMIR Mhealth Uhealth

View full text Add to dashboard Cite

show abstract

“…Although we previously covered some recent applications for medication adherence monitoring [59] that rely on modalities such as sensor networks and proximity sensing, there is still a lack of comprehensive state-of-the-art survey studies concerning the recent medication adherence monitoring approaches. The main objective of this paper is to explore this topic further by extending the discussion on the monitoring systems, expanding the list of surveyed papers, taking account of other medication monitoring systems such as ingestible biosensors, and discussing the trade-offs of each technology in multiple dimensions.…”

Section: Related Workmentioning

confidence: 99%

A Review of Medication Adherence Monitoring Technologies

Aldeer

Javanmard

Martin

2018

ASI

Self Cite

113

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Medication non-adherence is a prevalent, complex problem. Failure to follow medication schedules may lead to major health complications, including death. Proper medication adherence is thus required in order to gain the greatest possible drug benefit during a patient's treatment. Interventions have been proven to improve medication adherence if deviations are detected. This review focuses on recent advances in the field of technology-based medication adherence approaches and pays particular attention to their technical monitoring aspects. The taxonomy space of this review spans multiple techniques including sensor systems, proximity sensing, vision systems, and combinations of these. As each technique has unique advantages and limitations, this work describes their trade-offs in accuracy, energy consumption, acceptability and user's comfort, and user authentication.

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“…The need for objective and reliable ways to confirm medication use has driven the development of various tracking methods, including patient self-reports, adherence-reporting mobile apps, pill counts, pharmacy prescription refill rates, electronic pill dispensers, and other solutions—but none have been optimized, and many are not reliable [ 16 ]. Digital pill systems, in contrast, have demonstrated a high rate of accuracy, with a study showing a 99.4% adherence rate across 2824 digital pill ingestions that were tracked [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

A Novel Digital Pill System for Medication Adherence Measurement and Reporting: Usability Validation Study

Baumgartner¹,

Jr²,

Rukavina³

et al. 2021

JMIR Hum Factors

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Background Medication nonadherence is a costly problem that is common in clinical use and clinical trials alike, with significant adverse consequences. Digital pill systems have proved to be effective and safe solutions to the challenges of nonadherence, with documented success in improving adherence and health outcomes. Objective The aim of this human factors validation study is to evaluate a novel digital pill system, the ID-Cap System from etectRx, for usability among patient users in a simulated real-world use environment. Methods A total of 17 patients with diverse backgrounds who regularly take oral prescription medications were recruited. After training and a period of training decay, the participants were asked to complete 12 patient-use scenarios during which errors or difficulties were logged. The participants were also interviewed about their experiences with the ID-Cap System. Results The participants ranged in age from 27 to 74 years (mean 51 years, SD 13.8 years), and they were heterogeneous in other demographic factors as well, such as education level, handedness, and sex. In this human factors validation study, the patient users completed 97.5% (196/201) of the total use scenarios successfully; 75.1% (151/201) were completed without any failures or errors. The participants found the ID-Cap System easy to use, and they were able to accurately and proficiently record ingestion events using the device. Conclusions The participants demonstrated the ability to safely and effectively use the ID-Cap System for its intended use. The ID-Cap System has great potential as a useful tool for encouraging medication adherence and can be easily implemented by patient users.

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Medication adherence monitoring using modern technology

Cited by 15 publications

References 52 publications

Technologies for Medication Adherence Monitoring and Technology Assessment Criteria: Narrative Review

Technologies for Medication Adherence Monitoring and Technology Assessment Criteria: Narrative Review

A Review of Medication Adherence Monitoring Technologies

A Novel Digital Pill System for Medication Adherence Measurement and Reporting: Usability Validation Study

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