Medication Adherence to Type 2 Diabetic Patients Hospitalized at a Tertiary Care Hospital in Bangladesh

Rana, Mohammad Masud; Islam, Mohammad Shariful; Akter, Jotsna; Khatun, Shanzida

doi:10.17532/jhsci.2019.818

Cited by 7 publications

(11 citation statements)

References 35 publications

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“…A study implied that patients typically perceived to be healthy including those who were new to diabetes and on few other medications, may be at risk for non-adherence 12 . Although there were studies showing that patients with comorbidities may have worse medication compliance 12 , 17 , our subgroup analysis revealed those with high CIC or DCSI had better compliance. This might be due to the wide coverage and extremely low co-payment of our National Health Insurance policy.…”

Section: Discussioncontrasting

confidence: 55%

Importance of medication adherence in treatment needed diabetic retinopathy

Kao

Hsieh

Lee

et al. 2021

Sci Rep

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We aim to investigate the role of medication adherence history in treatment needed diabetic retinopathy (TNDR). We conducted a retrospective nested case–control study using 3 population-based databases in Taiwan. The major one was the 2-million-sample longitudinal health and welfare population-based database from 1997 to 2017, a nationally representative random sample of National Health Insurance Administration enrolled beneficiaries in 2010 (LHID2010). The national death registry and national cancer registry were also checked to verify the information. The outcome was defined as the TNDR. The Medication possession ratio (MPR) was defined as the ratio of total days of diabetes mellitus (DM) medication supply divided by total observation days. MPR ≥ 80% was proposed as good medication adherence. The association of MPR and the TNDR was analyzed. Other potential confounders and MPR ratio were also evaluated. A total of (n = 44,628) patients were enrolled. Younger aged, male sex and patients with less chronic illness complexity or less diabetes complication severity tend to have poorer medication adherence. Those with severe comorbidity or participating pay-for-performance program (P4P) revealed better adherence. No matter what the characteristics are, patients with good MPR showed a significantly lower likelihood of leading to TNDR after adjustment with other factors. The protection effect was consistent for up to 5 years. Good medication adherence significantly prevents treatment needed diabetic retinopathy. Hence, it is important to promote DM medication adherence to prevent risks of diabetic retinopathy progression, especially those who opt to have low medication adherence.

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Section: Discussioncontrasting

confidence: 55%

Importance of medication adherence in treatment needed diabetic retinopathy

Kao

Hsieh

Lee

et al. 2021

Sci Rep

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“…al reported that 25.9% of diabetes patients in a tertiary hospital sometimes forgot to take their medications, while 1.8% often forgot. 29 Our findings of low medication adherence are in line with a previous report from India that found the prevalence of low medication adherence to be 51.7% using the MMAS tool. 34 However, the lack of standard measurements for medication adherence, the difference in the sample population, and the use of different definitions for glycemic control make comparisons between studies challenging.…”

Section: Discussionsupporting

confidence: 92%

“…38 Our study suggested that low medication adherence was significantly higher among younger people which is in line with a study by Rana et.al. 29 A similar study by Ahmad et al in patients with Type 2…”

Section: Discussionmentioning

confidence: 63%

“…26,27 Previous studies on diabetes medication adherence in Bangladesh did not use a validated tool 28 and had a small sample size (n = 112). 29 Therefore, we conducted this study to determine the level of medication adherence and examine the factors associated with poor medication adherence in patients with Type 2 diabetes mellitus attending a tertiary diabetes hospital in Bangladesh.…”

Section: Introductionmentioning

confidence: 99%

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Factors associated with low medication adherence in patients with Type 2 diabetes mellitus attending a tertiary hospital in Bangladesh

Islam

Uddin

et al. 2021

Lifestyle Medicine

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Background: Adherence to prescribed medication is essential for glycemic control and to delay the onset of complications. However, information on medication adherence among patients with Type 2 diabetes mellitus is sparse in Bangladesh. This study aimed to determine medication adherence and factors associated with low adherence in patients with Type 2 diabetes in Bangladesh. Methods: A cross-sectional study was conducted among 500 consecutive patients with Type 2 diabetes attending a tertiary hospital in Bangladesh between September 2013 and July 2014. Data were collected on sociodemographic and clinical characteristics, medication use and adherence, and blood tests for glycated hemoglobin. Medication adherence was assessed using the 8-item Morisky Medication Adherence Scale (score range 0-8), and a score < 6 was defined as low adherence. Multiple logistic regression modeling was used to investigate factors associated with low medication adherence. Results: The mean age ± standard deviation of the participants was 50.2 ± 10.2 years (56.2% females). Overall, 42.8% (95% confidence interval (CI): 38.5-47.2) of This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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“…This finding could be because younger patients take better care of their health to ensure a long healthy life, and the elderly seem to fear complications and mortality. This reported adherence rate was consistent with the previous findings [25,26]. Moreover, older patients who suffer from comorbidities should have more medicines on their prescription, and polypharmacy is a potential factor for medication nonadherence [27].…”

Section: Discussionsupporting

confidence: 91%

Treatment Noncompliance Level Among Patients with Type 2 Diabetes Mellitus: A Hospital Based Cross-Sectional Study in Bangladesh

Khan

Pulock²,

et al. 2022

Preprint

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Introduction: The consequence of good diabetic treatment depends on the patient's commitment to a large degree. Noncompliance leads to inadequacy of metabolic control, which strengthens the advancement and speeds up diabetic complications. The study's main goal was to assess the treatment noncompliance level among patients with type-2 diabetes mellitus (T2DM) in Bangladesh. Methodology: This descriptive cross-sectional study was conducted at Medical Center Hospital, Chattogram, Bangladesh. The study included two hundred and fifty-nine patients with T2DM. Data regarding sociodemographic factors, patients characteristics, medication factors, physician-related factors, and noncompliance were collected using a pretested and structured questionnaire. Treatment adherence was assessed by Morisky Medication Adherence Scales (MMAS-8). Data analyses were conducted on SPSS v23.0 Software. Results: The majority of the participants (56%) were in the 40-45 years of age group, followed by 32% in the older age group (>/=60 years), and 62.5% of them were male. One hundred and sixty eight (64.86%) patients were considered low adherent as per the response of the MMAS-8 scale (score <6), followed by 57 (22.0%) patients were regarded as high adherent (score 8) and 34 (13.13%) patients were considered medium adherent (score 6-7) to treatment. Observing the frequency distribution for noncompliance, financial concerns (32.3 %), forgetfulness (27.7%), a busy daily schedule (17.7%), and fear of antihyperglycemic drug side effects were all identified as significant explanations. On multivariate analysis, participants aged 60 years or more, monthly family incomes of <30,000BDT or 30,000 to 50,000 BDT, smoking, and uncontrolled glycemic status showed higher chances of noncompliance than their counterparts. Conclusion: Patient counseling and awareness programs may enhance treatment adherence among people with T2DM. Our findings will help physicians and public health workers to develop targeted strategies to increase awareness of the same among their patients.

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Medication Adherence to Type 2 Diabetic Patients Hospitalized at a Tertiary Care Hospital in Bangladesh

Cited by 7 publications

References 35 publications

Importance of medication adherence in treatment needed diabetic retinopathy

Importance of medication adherence in treatment needed diabetic retinopathy

Factors associated with low medication adherence in patients with Type 2 diabetes mellitus attending a tertiary hospital in Bangladesh

Treatment Noncompliance Level Among Patients with Type 2 Diabetes Mellitus: A Hospital Based Cross-Sectional Study in Bangladesh

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