Medication Overuse in Children and Adolescents

Gelfand, Amy A.; Goadsby, PJ

doi:10.1007/s11916-014-0428-1

Cited by 44 publications

(41 citation statements)

References 42 publications

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“…Lower headache frequency per month was significantly associated with a better clinical response in patients with episodic headache but not chronic headache. Although the adverse effect of overuse of medication on treatment response in our study was not significant, the achievement of a P value equal to .05 may suggest a trend, consistent with earlier studies showing that medication overuse is an important cause of chronic migraine and associated with lower efficacy of migraine preventive medication …”

Section: Discussionsupporting

confidence: 90%

“…Although the adverse effect of overuse of medication on treatment response in our study was not significant, the achievement of a P value equal to .05 may suggest a trend, consistent with earlier studies showing that medication overuse is an important cause of chronic migraine and associated with lower efficacy of migraine preventive medication. 17,18 We found no association between migraine with or without aura and treatment response. By contrast, a study in adults reported a lesser effect of sumatriptan as acute therapy for migraine attacks with aura than without aura.…”

Section: Discussioncontrasting

confidence: 53%

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Factors Influencing Response to Pharmacologic Treatment of Migraine in a Pediatric Headache Clinic

et al. 2016

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Section: Discussionsupporting

confidence: 90%

Section: Discussioncontrasting

confidence: 53%

Factors Influencing Response to Pharmacologic Treatment of Migraine in a Pediatric Headache Clinic

et al. 2016

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“…Chiappedi and Balottin [Chiappedi and Balottin, 2014], and Gelfand and Goadsby [Gelfand and Goadsby, 2014] recently reviewed the literature on MOH in children and adolescents and showed that population-based epidemiologic studies are sparse (with data available only from Norway, Taiwan, and the US) but MOH is commonly encountered in the clinical setting.…”

Section: Population Prevalence Of Mohmentioning

confidence: 99%

“…There is disagreement on how to discontinue medication (gradual reduction versus complete withdrawal); and when to use preventive medication (early in the treatment period or after medication reduction). There is sparse data on best practice for the treatment of MOH in children [Gelfand and Goadsby, 2014]. Comorbidity MOH has been linked to comorbid psychiatric disorders [Atasoy et al 2012;Fuh and Wang, 2012;Radat and Lanteri-Minet, 2012].…”

Section: Treatment Protocolmentioning

confidence: 99%

Medication-overuse headache: a perspective review

Westergaard

Munksgaard

Bendtsen

et al. 2016

Therapeutic Advances in Drug Safety

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Medication-overuse headache (MOH) is a debilitating condition in which frequent and prolonged use of medication for the acute treatment of pain results in the worsening of the headache. The purpose of this paper is to review the most recent literature on MOH and discuss future avenues for research. MOH accounts for a substantial share of the global burden of disease. Prevalence is often reported as 1-2% but can be as high as 7% overall, with higher proportions among women and in those with a low socioeconomic position. Management consists of withdrawing pain medication, focusing on prophylactic and nonmedical treatments, and limiting acute symptomatic medication. Stress reduction and lifestyle interventions may support the change towards rational pain medication use. Support, follow up, and education are needed to help patients through the detoxification period. There is fertile ground for research in MOH epidemiology, pathophysiology, and neuroimaging. Randomized and long-term follow-up studies on MOH treatment protocols are needed. Further focused research could be of major importance for global health.

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“…The age span is 3-18 years depending on the disorder. The main consequences of frequent headaches in children and adolescents are more frequent school absences; disturbed health-related quality of life (HRQOL) [5] and a risk of medication overuse [6].…”

Section: Introductionmentioning

confidence: 99%

Children and Adolescents with Primary Tension‐Type Headaches: Research and Practice Perspectives for Non‐ Pharmacological Interdisciplinary Headache Service

Tornøe¹

2017

Current Perspectives on Less-Known Aspects of Headache

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Background: Children and adolescents with frequent and chronic primary headaches are, with a prevalence of 2-23% depending on diagnosis, age, sex and frequency, a global health concern. Research on non-pharmacological treatment outcomes is sparse. Headache service faces a challenge because possible sensitisation of pain pathways can affect outcomes leading to a delay in becoming symptom free or being cured. Method:This chapter provides a narrative review of research containing suggestions for relevant focus areas for professionals who work with children and their parents in the process of self-care. Conclusions:Research supports that increased pericranial tenderness in children with consistent primary tension-type headache is a consequence of activated pain pathways and relevant for clinical assessment. Tension patterns, posture, muscle balance and strength in the neck/shoulder region are areas of importance for minimising the triggering of input to the nociceptive system. Lifestyle factors such as sleep, nutrition, stress and tension regulation, posture and ergonomics, physical activity (PA) and exercise are a key part of non-pharmacological team service. Empowering patient education that provides children and adolescents with the knowledge and drive to persistently pursue healthy lifestyle changes is the basis for potentially successful outcomes in terms of ethical, cultural and educational issues.

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Medication Overuse in Children and Adolescents

Cited by 44 publications

References 42 publications

Factors Influencing Response to Pharmacologic Treatment of Migraine in a Pediatric Headache Clinic

Factors Influencing Response to Pharmacologic Treatment of Migraine in a Pediatric Headache Clinic

Medication-overuse headache: a perspective review

Children and Adolescents with Primary Tension‐Type Headaches: Research and Practice Perspectives for Non‐ Pharmacological Interdisciplinary Headache Service

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