Medication review of community-dwelling seniors using intensified home-care service

Inappropriate Medication in Non‐Hospitalized Patients With Renal Insufficiency: A Systematic Review

“…One study sample comprised data from nursing home residents as well as additional outpatient data . The remaining studies were based on data from community pharmacies, general practices, or other outpatient medical records . The population samples studied included data from 90 to 462,405 individuals.…”

“…Except for two of the studies, all other studies included had particular inclusion or exclusion criteria regarding age, specific diagnoses, or creatinine clearance (Table ). Of those, the majority (N = 14) had age restrictions . Eight of the studies were restricted to individuals who were either not on dialysis or whose eGFR was below a specific cut‐off value .…”

“…Recommendations for adjustment of dosage or potential contraindications in renal insufficiency were assessed from varying sources such as online databases, drug dictionaries, or guidelines . Two articles provided no further information about underlying sources …”

“…Most of the studies were conducted in the United States (n = 8; 41.2%), 3,15,[26][27][28][29][30][31] followed by Germany (n = 3; 17.6%) 6,32,33 and Australia (n = 2; 11.8%) 5,34 (Table S2). One study each was from France, 35 Belgium, 36 the Netherlands, 37 Spain, 38 and Canada.…”

“…5 The remaining studies were based on data from community pharmacies, 15,27,31,37,38 general practices, 6 or other outpatient medical records. 26,28,30,33,35,36 The population samples studied included data from 90 to 462,405 individuals.…”